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High Frequencies of PD-1+TIM3+TIGIT+CTLA4+ Functionally Exhausted SARS-CoV-2-Specific CD4+ and CD8+ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

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Authors

Pierre-Gregoire Coulon,Swayam Prakash

Nisha Dhanushkodi,Ruchi Srivastava,Latifa Zayou,Delia Tifrea,Robert Edwards,Cesar Figueroa,Sebastian Schubl,Lanny Hsieh,Anthony Nesburn,Baruch Kuppermann,Elmostafa Bahraoui,Hawa Vahed,Daniel Gil,Trevor Jones,Jeffrey Ulmer,Lbachir BenMohamed,Rakesh Srivastava

+17 authors

Journal

bioRxiv (Cold Spring Harbor Laboratory)

Published

Jan 31, 2022

DOI

10.1101/2022.01.30.478343

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