When trying to solve classification or time-series prediction problem statements by the application of Artificial Neural Networks (ANNs), commonly applied structures like feed forward or recurrent Multi-Layer Perceptrons (MLP) characteristically tend to come up with bad performance and accuracy. This is especially the case when dealing with manifold datasets containing numerous input (predictors) and/or targetattributes and independent from the applied learning methods, activation functions, biases, etc... The cortical ANN, inspired by theoretical aspects of the human consciousness and its signal processing, is an ANN structure having been developed during the research phase of the “System applying High Order Computational Intelligence” (SHOCID) project. Due to its structure, redundancy and error-tolerance is being created, which helps to elude the latterly mentioned problems. Within this elaboration, the cortical ANN is being introduced, as well as an algorithm for evolving this special ANN types' structure until the most suitable solution has been detected.