Context. More complete knowledge of galaxy evolution requires understanding the process of star formation and the interaction between the interstellar radiation field and interstellar medium (ISM) in galactic environments traversing a wide range of physical parameter space. We focus on the impact of massive star formation on the surrounding low metallicity ISM in 30 Doradus in the Large Magellanic Cloud (LMC). A low metal abundance, which can characterizes some galaxies of the early Universe, results in less ultraviolet (UV) shielding for the formation of the molecular gas necessary for star formation to proceed. The half-solar metallicity gas in this region is strongly irradiated by the super star cluster R136, making it an ideal laboratory to study the structure of the ISM in an extreme environment.
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