Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

Crispin Hiley,Marcin Skrzypski,Alexander Frankell,Björn Bakker,Thomas Watkins,Aleksandra Markovets,Jonathan Dry,Andy Brown,Jasper Aart,Hilda Bos,Diana Spierings,Dahmane Oukrif,Marco Novelli,Turja Chakrabarti,Adam Rabinowitz,Laila Hassou,Saskia Litière,D. Kerr,Lisa Tan,Gavin Kelly,David Moore,Matthew Renshaw,Subramanian Venkatesan,William Hill,Ariana Huebner,Carlos Martínez‐Ruiz,James Black,Wei Wu,Mihaela Angelova,Nicholas McGranahan,Julian Downward,Juliann Chmielecki,Carl Barrett,Kevin Litchfield,Su Chew,Collin Blakely,Elza Bruin,Floris Foijer,Karen Vousden,Trever Bivona,J.F. Lester,Amrita Bajaj,Apostolos Nakas,Azmina Sodha-Ramdeen,Mohamad Tufail,Molly Scotland,Rebecca Boyles,Sridhar Rathinam,Claire Wilson,Domenic Marrone,Sean Dulloo,Dean Fennell,Gurdeep Matharu,Jacqui Shaw,Ekaterini Boleti,Heather Cheyne,Mohammed Khalil,Shirley Richardson,Tracey Cruickshank,Gillian Price,Keith Kerr,Sarah Benafif,Jack French,Kayleigh Gilbert,Babu Naidu,Akshay Patel,Aya Osman,Carol Enstone,Gerald Langman,Helen Shackleford,Madava Djearaman,Salma Kadiri,Gary Middleton,Angela Leek,Jack Hodgkinson,Nikki Totton,Ángeles Montero,Elaine Smith,Eustace Fontaine,Felice Granato,António Paiva-Correia,Juliette Novasio,Kendadai Rammohan,Leena Joseph,Paul Bishop,Rajesh Shah,Stuart Moss,Vijay Joshi,Philip Crosbie,Kate Brown,Mathew Carter,Anshuman Chaturvedi,Pedro Oliveira,Colin Lindsay,Fiona Blackhall,Matthew Krebs,Yvonne Summers,Alexandra Clipson,Jonathan Tugwood,Alastair Kerr,Dominic Rothwell,Caroline Dive,Hugo Aerts,Roland Schwarz,Tom Kaufmann,Gareth Wilson,Rachel Rosenthal,Peter Loo,Nicolai Birkbak,Zoltán Szállási,Judit Kisistók,Mateo Sokač,Roberto Salgado,Miklós Dióssy,Jonas Demeulemeester,Abigail Bunkum,Angela Dwornik,Alastair Magness,Andrew Rowan,Angeliki Karamani,Antonia Toncheva,Benny Chain,Carla Castignani,C. Bailey,Christophe Dessimoz,Clare Puttick,Clare Weeden,Claudia Lee,Corentin Richard,Cristina Naceur‐Lombardelli,David Pearce,Despoina Karagianni,Dhruva Biswas,Dina Levi,Elizabeth Cadieux,Emilia Lim,Emma Colliver,Emma Nye,Felip Gálvez-Cancino,Francisco Gimeno-Valiente,George Kassiotis,Georgia Stavrou,Gerasimos-Theodoros Mastrokalos,Helen Lowe,Ignacio Matos,Imran Noorani,Jacki Goldman,James Reading,Jayant Rane,Jérôme Nicod,John Hartley,Karl Peggs,Katey Enfield,Kayalvizhi Selvaraju,Kerstin Thol,Kevin Ng,Kezhong Chen,Krijn Dijkstra,Kristiana Grigoriadis,Krupa Thakkar,Leah Ensell,Cinzia Allegrucci,Maria Litovchenko,Mariam Jamal‐Hanjani,Mariana Sunderland,Matthew Huska,Mark Hill,Michelle Dietzen,Michelle Leung,Mickael Escudero,Miljana Tanić,M Sivakumar,Olga Chervova,Olivia Lucas,Oriol Pich,Othman Al‐Sawaf,Paulina Prymas,Philip Hobson,Piotr Pawlik,Richard Stone,Robert Bentham,Roberto Vendramin,Sadegh Saghafinia,Samuel Gamble,Selvaraju Veeriah,Seng Ung,Sergio Quezada,Sharon Vanloo,Sonya Hessey,Sophia Ward,Simon Harries,Stefan Boeing,Stephan Beck,Supreet Bola,Takahiro Karasaki,Tamara Denner,Teresa Marafioti,T. Jones,Victoria Spanswick,Vittorio Barbè,Wei-Ting Lu,Wing Liu,Yin Wu,Yutaka Naito,Zoe Ramsden,Catarina Veiga,G. Royle,Charles‐Antoine Collins‐Fekete,Francesco Fraioli,Paul Ashford,Martin Förster,Siow Lee,Elaine Borg,Mary Falzon,Dionysis Papadatos-Pastos,James Wilson,Tanya Ahmad,Alexander Procter,Asia Ahmed,Magali Taylor,Arjun Nair,David Lawrence,Davide Patrini,Neal Navani,Ricky Thakrar,Sam Janes,Emilie Hoogenboom,Fleur Monk,James Holding,Junaid Choudhary,Kunal Bhakhri,Marco Scarci,Pat Gorman,Reena Khiroya,Robert Stephens,Yien Wong,Zoltán Káplár,Steve Bandula,Allan Hackshaw,Anne-Marie Hacker,Abigail Sharp,Sean Smith,Harjot Dhanda,Camilla Pilotti,Rachel Leslie,Anca Grapa,Hanyun Zhang,Khalid AbdulJabbar,Xiaoxi Pan,Yinyin Yuan,David Chuter,Mairead MacKenzie,Serena Chee,Aiman Alzetani,Judith Cave,Jennifer Richards,Eric Lim,Sally Dewhurst,Simon Jordan,Alexandra Rice,Hilgardt Raubenheimer,Harshil Bhayani,Lyn Ambrose,Anand Devaraj,Hema Chavan,Sofina Begum,Silviu Buderi,Daniel Kaniu,Mpho Malima,Sarah Booth,Andrew Nicholson,Nadia Fernandes,Pratibha Shah,Chiara Proli,Madeleine Hewish,Sarah Danson,Michael Shackcloth,Lily Robinson,Peter Russell,Kevin Blyth,Andrew Kidd,Craig Dick,John Quesne,Alan Kirk,Mo Asif,Rocco Bilancia,Nikos Kostoulas,Mathew Thomas,Robert Hynds,Nnennaya Kanu,Simone Zaccaria,Eva Grönroos,Charles Swanton,S. Venkatesan,Carlos Martínez-Ruiz,Benjamin Chain