The IMRiS Trial: A Phase II Study of Intensity-Modulated Radiotherapy in Extremity Soft Tissue Sarcoma

Abstract

Primary soft tissue sarcoma (STS) is rare, with many tumors occurring in extremities. Local management is limb-sparing surgery and preoperative/postoperative radiation therapy (RT) for patients at high risk of local recurrence. We prospectively investigated late normal tissue toxicity and limb function observed after intensity modulated RT (IMRT) in extremity STS.