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IL-33-dependent NF-κB activation inhibits apoptosis and d... | ResearchHub

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Cancer Research

DOI

10.1016/j.cyto.2024.156672

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IL-33-dependent NF-κB activation inhibits apoptosis and drives chemoresistance in acute myeloid leukemia

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Authors

Muxia Yan

Muxia Yan•Xue-Xin Chen•Yiqian Wang

Published

June 8, 2024

Abstract

Despite recent advances in therapeutic regimens, the prognosis of acute myeloid leukemia (AML) remains poor. Following our previous finding that interleukin-33 (IL-33) promotes cell survival along with activated NF-κB in AML, we further investigated the role of NF-κB during leukemia development.

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Support the authors with ResearchCoin

Journal

Topics

Cancer Research

DOI

10.1016/j.cyto.2024.156672