Design, synthesis, and structure–activity relationship studies of 6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole derivatives as necroptosis inhibitors
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Authors
Zhe Jin
Zhe Jin•Yang Dai•Hefeng Zhang
Published
January 1, 2024
Abstract
This study reported a series of 6,7-dihydro-5 H -pyrrolo[1,2- b ][1,2,4]triazole derivatives with potent RIPK1 inhibitory activity and anti-necroptotic activity in both human and mouse cellular assays.
