The extent to which the geographic diversity of the U.S. plays a significant role in melanoma incidence and mortality over time has not been precisely characterized. We obtained age-adjusted melanoma data for the 50 states between the years 2001-2019 from the SEER registry and performed hierarchical clustering (complete linkage, Euclidean space) to uncover geotemporal trend groups over 2 decades. While there was a global increase in incidence during this time (b
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