CancerVolume 77, Issue 7 p. 1254-1262 Original ArticleFree Access Surgical resection of colorectal carcinoma metastases to the liver: A prognostic scoring system to improve case selection, based on 1568 patients Bernard Nordlinger M.D., Corresponding Author Bernard Nordlinger M.D. Centre de Chirurgie Digestive, Hôpital Saint Antoine, Paris, FranceCentre de Chirurgie Digestive, Hôpital Saint Antoine, 184, rue du Faubourg Saint Antoine, F-75571-PARIS Cedex 12, France===Search for more papers by this authorMarguerite Guiguet M.D., Marguerite Guiguet M.D. INSERM U263, Hôpital Saint Antoine, Paris, FranceSearch for more papers by this authorJean-Christophe Vaillant M.D., Jean-Christophe Vaillant M.D. Centre de Chirurgie Digestive, Hôpital Saint Antoine, Paris, FranceSearch for more papers by this authorPierre Balladur M.D., Pierre Balladur M.D. Centre de Chirurgie Digestive, Hôpital Saint Antoine, Paris, FranceSearch for more papers by this authorKarim Boudjema M.D., Karim Boudjema M.D. Service de Chirurgie Générale et Endocrinienne, Hôpital de Hautepierre, Strasbourg, FranceSearch for more papers by this authorPhilippe Bachellier M.D., Philippe Bachellier M.D. Service de Chirurgie Générale et Endocrinienne, Hôpital de Hautepierre, Strasbourg, FranceSearch for more papers by this authorDaniel Jaeck M.D., Daniel Jaeck M.D. Service de Chirurgie Générale et Endocrinienne, Hôpital de Hautepierre, Strasbourg, FranceSearch for more papers by this author Association Française de Chirurgie, Association Française de Chirurgie Centre de Chirurgie Digestive, Hôpital Saint Antoine, Paris, FranceSearch for more papers by this author Bernard Nordlinger M.D., Corresponding Author Bernard Nordlinger M.D. Centre de Chirurgie Digestive, Hôpital Saint Antoine, Paris, FranceCentre de Chirurgie Digestive, Hôpital Saint Antoine, 184, rue du Faubourg Saint Antoine, F-75571-PARIS Cedex 12, France===Search for more papers by this authorMarguerite Guiguet M.D., Marguerite Guiguet M.D. INSERM U263, Hôpital Saint Antoine, Paris, FranceSearch for more papers by this authorJean-Christophe Vaillant M.D., Jean-Christophe Vaillant M.D. Centre de Chirurgie Digestive, Hôpital Saint Antoine, Paris, FranceSearch for more papers by this authorPierre Balladur M.D., Pierre Balladur M.D. Centre de Chirurgie Digestive, Hôpital Saint Antoine, Paris, FranceSearch for more papers by this authorKarim Boudjema M.D., Karim Boudjema M.D. Service de Chirurgie Générale et Endocrinienne, Hôpital de Hautepierre, Strasbourg, FranceSearch for more papers by this authorPhilippe Bachellier M.D., Philippe Bachellier M.D. Service de Chirurgie Générale et Endocrinienne, Hôpital de Hautepierre, Strasbourg, FranceSearch for more papers by this authorDaniel Jaeck M.D., Daniel Jaeck M.D. Service de Chirurgie Générale et Endocrinienne, Hôpital de Hautepierre, Strasbourg, FranceSearch for more papers by this author Association Française de Chirurgie, Association Française de Chirurgie Centre de Chirurgie Digestive, Hôpital Saint Antoine, Paris, FranceSearch for more papers by this author First published: 1 April 1996 https://doi.org/10.1002/(SICI)1097-0142(19960401)77:7<1254::AID-CNCR5>3.0.CO;2-ICitations: 1,200AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract BACKGROUND Five-year survival rates after resection of liver metastases from colorectal carcinoma are close to 25%. Recurrences occur in two-thirds of the patients after surgery. Selection of patients likely to benefit from surgery remains controversial and subjective. METHODS Data from 1568 patients with resected liver metastases from colorectal carcinoma were collected. The prognostic value of different factors was studied through uni- and multivariate analyses. A scoring system was developed including the most relevant factors. RESULTS Two- and 5-year survival rates were 64% and 28%, respectively, and were affected by: age; size of largest metastasis or CEA level; stage of the primary tumor; disease free interval; number of liver nodules; and resection margin. Giving one point to each factor, the population was divided into three risk groups with different 2-year survival rates: 0–2 (79%), 3–4 (60%), 5–7 (43%). CONCLUSIONS A simple prognostic scoring system was proposed to evaluate the chances for cure of patients after resection of liver metastases from colorectal carcinoma. The comparison between expected survival and estimated operative risk can help determine on an objective basis whether surgery is worthwhile. This system needs further prospective validation. Cancer 1996;77:1254-62. References 1 Fortner JG, Silva JS, Golbey RB, Cox EB, MacLean J. Multivariate analysis of a personal series of 247 consecutive patients with liver metastases from colorectal cancer. 1-Treatment by hepatic resection. Ann Surg 1984; 199: 306– 16. 2 August DA, Sugarbaker PH, Ottow RT, Gianola FJ, Schneider PD. Hepatic resection of colorectal metastases-Influence of clinical factors and adjuvant intraperitoneal 5-Fluorouracil via Tenckhoff catheter on survival. 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