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SomaticCALRMutations in Myeloproliferative Neoplasms with NonmutatedJAK2
Authors
Jyoti Nangalia,Charles Massie
E. Baxter,Francesca Nice,Gunes Gundem,David Wedge,Edward Avezov,J. Li,Karoline Kollmann,David Kent,Aziz Aziz,Anna Godfrey,Jonathan Hinton,Iñigo Martincorena,Peter Loo,Amy Jones,Paola Guglielmelli,Patrick Tarpey,Heather Harding,John Fitzpatrick,Calum Goudie,Christina Ortmann,Stephen Loughran,Keiran Raine,Dan Jones,Adam Butler,Joshua Stuart,Sarah O’Meara,Karen McLaren,Michele Bianchi,Yvonne Silber,Dimitra Dimitropoulou,David Bloxham,Laura Mudie,Mark Maddison,Ben Robinson,Clodagh Keohane,Cathy MacLean,Kate Hill,Kim Orchard,Sheral Tauro,Ming‐Qing Du,Mel Greaves,David Bowen,Brian Huntly,Claire Harrison,Nicholas Cross,David Ron,Alessandro Vannucchi,Elli Papaemmanuil,Peter Campbell,Anthony Green
+50 authors
,Stuart McLarenPublished
Dec 10, 2013
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Abstract
Somatic mutations in the Janus kinase 2 gene (JAK2) occur in many myeloproliferative neoplasms, but the molecular pathogenesis of myeloproliferative neoplasms with nonmutated JAK2 is obscure, and the diagnosis of these neoplasms remains a challenge.
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