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Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

Authors
W. Linehan,Paul Spellman
Christopher Ricketts,Chad Creighton,Suzanne Fei,Caleb Davis,David Wheeler,Bradley Murray,Laura Schmidt,Cathy Vocke,Myron Peto,Abdullah Mamun,Eve Shinbrot,Anurag Sethi,Samira Brooks,W. Rathmell,Angela Brooks,Katherine Hoadley,A. Robertson,Denise Brooks,Reanne Bowlby,Sara Sadeghi,Hui Shen,Daniel Weisenberger,Moiz Bootwalla,Lars Feuerbach,Peter Laird,Andrew Mungall,Gordon Saksena,Scott Haake,Jun Li,Han Liang,Yiling Lu,Gordon Mills,Rehan Akbani,Mark Leiserson,Benjamin Raphael,Pavana Anur,Donald Bottaro,Laurence Albigès,Nandita Barnabas,Toni Choueiri,Bogdan Czerniak,A. Hakimi,Thai Ho,James Hsieh,Michael Ittmann,William Kim,Bhavani Krishnan,Maria Merino,Kenna Shaw,Victor Reuter,Ed Reznik,Carl Shelley,Brian Shuch,Sabina Signoretti,L. Sylvia,Pheroze Tamboli,George Thomas,Satish Tickoo,Karen Burnett,Daniel Crain,Johanna Gardner,Kevin Lau,David Mallery,Scott Morris,Joseph Paulauskis,Robert Penny,Candace Shelton,W. Shelton,Mark Sherman,Eric Thompson,Peggy Yena,Melissa Avedon,Jay Bowen,Julie Gastier-Foster,Mark Gerken,Kristen Leraas,Tara Lichtenberg,Nilsa Ramirez,T.E.J. Santos,Lisa Wise,Erik Zmuda,John Demchok,Ina Felau,Carolyn Hutter,Margi Sheth,Heidi Sofia,Roy Tarnuzzer,Zhining Wang,Liming Yang,Jean Zenklusen,Jiashan Zhang,Brenda Ayala,Julien Baboud,Sudha Chudamani,Jia Liu,Laxmi Lolla,Rashi Naresh,Todd Pihl,Qiang Sun,Yunhu Wan,Ye Wu,Adrian Ally,Miruna Balasundaram,Saianand Balu,Rameen Beroukhim,Tom Bodenheimer,Christian Buhay,Yaron Butterfield,Rebecca Carlsen,Scott Carter,Hsu Chao,Eric Chuah,Amanda Clarke,Kyle Covington,Mahmoud Dahdouli,Ninad Dewal,Noreen Dhalla,HarshaVardhan Doddapaneni,Jennifer Drummond,Stacey Gabriel,Richard Scolyer,Ranabir Guin,Walker Hale,Alicia Hawes,D. Hayes,Robert Holt,Alan Hoyle,Stuart Jefferys,Steven Jones,Corbin Jones,Dinesh Kumar,Christie Kovar,Lora Lewis,Jia Li,Yussanne Ma,Marco Marra,Michael Mayo,Shaowu Meng,Matthew Meyerson,Piotr Mieczkowski,Richard Moore,Donna Morton,Lisle Mose,Donna Muzny,Joel Parker,Charles Perou,Jeffrey Roach,Jacqueline Schein,Steven Schumacher,Yan Shi,Janae Simons,Payal Sipahimalani,Tara Skelly,Matthew Soloway,Carrie Sougnez,Angela Tam,Donghui Tan,Nina Thiessen,Umadevi Veluvolu,Min Wang,Matthew Wilkerson,Tina Wong,Junyuan Wu,Xi Liu,Jane Zhou,Jason Bedford,Fengju Chen,Yao Fu,Mark Gerstein,David Haussler,Katayoon Kasaian,Phillip Lai,Shiyun Ling,Amie Radenbaugh,David Bowtell,John Weinstein,Jingchun Zhu,Monique Albert,Iakovina Alexopoulou,Jeremiah Andersen,J. Auman,John Bartlett,Sheldon Bastacky,Julie Bergsten,Michael Blute,Lori Boice,Roni Bollag,Jeff Boyd,Erik Castle,Ying‐Bei Chen,John Cheville,Erin Curley,Benjamin Davies,April DeVolk,Rajiv Dhir,Laura Dike,John Eckman,Jay Engel,Jodi Harr,Ronald Hrebinko,Mei Huang,Lori Huelsenbeck-Dill,Mary Iacocca,Bruce Jacobs,Michael Lobis,Jodi Maranchie,Scott McMeekin,Jerome Myers,Joel Nelson,Jeremy Parfitt,A.V. Parwani,Nicholas Petrelli,Brenda Rabeno,Somak Roy,Andrew Salner,Joel Slaton,Melissa Stanton,R. Thompson,Leigh Thorne,Kelinda Tucker,Paul Weinberger,Cynthia Winemiller,Leigh Zach,Rosemary Zuna
+224 authors
,María Merino
Published
Nov 4, 2015
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Abstract

Papillary renal-cell carcinoma, which accounts for 15 to 20% of renal-cell carcinomas, is a heterogeneous disease that consists of various types of renal cancer, including tumors with indolent, multifocal presentation and solitary tumors with an aggressive, highly lethal phenotype. Little is known about the genetic basis of sporadic papillary renal-cell carcinoma, and no effective forms of therapy for advanced disease exist.

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