Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain
Authors
Ivan Alić,
Pollyanna GohAoife Murray,
Erik Portelius,
Eleni Gkanatsiou,
Gillian Gough,
Kin Mok,
David Koschut,
Reinhard Brunmeir,
Yee Yeap,
Niamh O’Brien,
Jurgen Groet,
Xiaowei Shao,
Steven Havlicek,
N Dunn,
Hlin Kvartsberg,
Gunnar Brinkmalm,
Rosalyn Hithersay,
Carla Startin,
Sarah Hamburg,
Margaret Phillips,
Konstantin Pervushin,
Mark Turmaine,
David Wallon,
Anne Rovelet-Lecrux,
Hilkka Soininen,
Emanuela Volpi,
Joanne Martin,
Jia Foo,
David Becker,
Agueda Rostagno,
Jorge Ghiso,
Željka Krsnik,
Goran Šimić,
Ivica Kostović,
Dinko Mitrečić,
LonDownS Consortium,
Paul Francis,
Kaj Blennow,
Andre Strydom,
John Hardy,
Henrik Zetterberg,
Dean Nižetić,
Jürgen Groet,
Nick Dunn,
Anne Rovelet‐Lecrux +44 authors
,
André Strydom Tip Tip