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New insights into the genetic etiology of Alzheimer’s disease and related dementias

Authors
Céline Bellenguez,Fahri Küçükali
Iris Jansen,Luca Kleineidam,Sonia Moreno–Grau,Najaf Amin,Adam Naj,Rafael Campos‐Martin,Benjamin Grenier‐Boley,Víctor Andrade,Peter Holmans,Anne Boland,Vincent Damotte,Sven Lee,Marcos Costa,Teemu Kuulasmaa,Qiong Yang,Itziar Rojas,Joshua Sonnen,Amber Yaqub,Ivana Nedeljković,Julien Chapuis,Shahzad Ahmad,Vilmantas Giedraitis,Dag Aarsland,Pablo García‐González,Carla Abdelnour,Emilio Alarcón‐Martín,Daniel Alcolea,Montserrat Alegret,Ignacio Álvarez,Victoria Álvarez,Nicola Armstrong,Anthoula Tsolaki,Carmen Antúnez,Ildebrando Appollonio,Marina Arcaro,Silvana Archetti,Alfonso Pastor,Beatrice Arosio,Lavinia Athanasiu,Henri Bailly,Nerisa Banaj,Miquel Baquero,Bernadette McGuinness,Alexa Beiser,Ana Pastor,Jennifer Below,Penelope Benchek,Luisa Benussi,Claudine Berr,Manuel Serrano‐Ríos,Valentina Bessi,Giuliano Binetti,Alessandra Bizarro,Rafael Blesa,Merçé Boada,Eric Boerwinkle,Barbara Borroni,Paola Bossù,Geir Bråthen,Jan Bressler,Catherine Bresner,Joseph Parisi,Keeley Brookes,Luis Brusco,Dolores Buiza‐Rueda,Katharina Bürger,Urho Kujala,William Bush,Miguel Calero,Laura Cantwell,Geneviève Chêne,Jaeyoon Chung,Michael Cuccaro,Ángel Carracedo,Roberta Ghidoni,Laura Cervera‐Carles,Camille Charbonnier,Hung‐Hsin Chen,Caterina Chillotti,Simona Ciccone,Jurgen Claassen,Christopher Clark,Elisa Conti,Anaïs Corma‐Gómez,Emanuele Costantini,Carlo Custodero,Delphine Bacq,Carolina Dalmasso,Antonio Daniele,Efthimios Dardiotis,Olivier Rouaud,Wei Gu,Kátia Lopes,Lot Witte,Stéphanie Debette,Jürgen Deckert,Teodoro Ser,Nicola Jones,Anita DeStefano,Martin Dichgans,Janine Diehl‐Schmid,Mónica Díez-Fairén,Paolo Rossi,Srdjan Djurovic,Emmanuelle Duron,Emrah Düzel,Carole Dufouil,Rik Vandenberghe,Sebastiaan Engelborghs,Valentina Escott‐Price,Ana Espinosa,Michael Ewers,Kelley Faber,Fabrizio Tagliavini,Sune Nielsen,David Fardo,Lucia Farotti,Chiara Fenoglio,Marta Fernández‐Fuertes,Raffaele Maletta,Catarina Ferreira,Evelyn Ferri,Bertrand Fin,Peter Fischer,Tormod Fladby,Klaus Fließbach,Bernard Fongang,Myriam Fornage,Juan Fortea,Chuanhai Cao,Silvia Fostinelli,Nick Fox,Emlio Franco-Macías,María Bullido,Ana Frank,Lutz Frölich,Brian Fulton‐Howard,Daniela Galimberti,José García‐Alberca,María Leciñana,Ruth Frikke‐Schmidt,Harald Hampel,Giaccone Giorgio,Alison Goate,Oliver Goldhardt,Duber Gomez-Fonseca,Caroline Graff,Giulia Grande,Timo Strandberg,Edna Grünblatt,Vilmundur Guðnason,Tamar Guetta-Baranés,Annakaisa Haapasalo,Georgios Hadjigeorgiou,Jonathan Haines,Olivier Hanon,John Hardy,Adelina Orellana,Lucrezia Hausner,Stefanie Heilmann‐Heimbach,Michael Heneka,Martin Herrmann,Per Selnes,Per Hoffmann,Clive Holmes,Henne Holstege,Raquel Vilas,Marc Hulsman,Jack Humphrey,Geert Biessels,Xueqiu Jian,Charlotte Johansson,Yuriko Katsumata,Patrick Kehoe,Susanne Moebus,Miia Turpeinen,Shireen Sindi,Anne Koivisto,Johannes Kornhuber,Mary Kosmidis,Walter Kukull,Pavel Kuksa,Amanda Cano,Amanda Kuzma,Carmen Lage,Erika Laukka,Lenore Launer,Chien‐Yueh Lee,Jenni Lehtisalo,Ondřej Lerch,Alberto Lleó,W.T. Longstreth,Oscar López,Seth Love,Malin Löwemark,Lauren Luckcuck,Kathryn Lunetta,Yiyi Ma,Catherine Macleod,Wolfgang Maier,Marco Spallazzi,Marta Marquié,Rachel Marshall,Eden Martin,Angel Montes,Carmen Rodríguez,Carlo Masullo,Richard Mayeux,Simon Mead,Patrizia Mecocci,Miguel Medina,Alun Meggy,Silvia Mendoza,Manuel Menéndez‐González,Laura Molina‐Porcel,Laura Montrreal,Fermín Moreno,Robert Bartha,Kevin Morgan,Markus Nöthen,Carolina Muchnik,Shubhabrata Mukherjee,Benedetta Nacmias,Børge Nordestgaard,Robert Olaso,Gemma Ortega,Alessandro Padovani,Paolo Caffarra,Ozren Polašek,Lucilla Parnetti,Pau Pástor,Gina Peloso,Jordi Pérez‐Tur,Pierre Péricard,Oliver Peters,Yolande Pijnenburg,Juan Pineda,Claudia Pisanu,Julius Popp,Daniëlle Posthuma,Josef Priller,Raquel Puerta,Olivier Quenez,Jesper Thomassen,Innocenzo Rainero,Farid Rajabli,Luís Real,Christian Toso,Christiane Reitz,Dolly Reyes‐Dumeyer,Steffi Riedel‐Heller,Peter Riederer,Eloy Rodríguez‐Rodríguez,Arvid Rongve,Matitee Rosende-Roca,José Royo,Elisa Rubino,María Sáez,Paraskevi Sakka,Ángela Sanabria,María Sánchez-Arjona,Florentino Sánchez-García,Pascual Sánchez-Juan,Raquel Sánchez‐Valle,Chloé Sarnowski,Claudia Satizábal,Michela Scamosci,Nikolaos Scarmeas,Philip Scheltens,Norbert Scherbaum,Martin Scherer,Anja Schneider,Geir Selbæk,Davide Seripa,Jin Sha,Alexey Shadrin,Olivia Skrobot,Gijsje Snijders,Hilkka Soininen,Vincenzo Solfrizzi,Alina Solomon,Yeunjoo Song,Sara Hägg,Óscar Sotolongo‐Grau,Gianfranco Spalletta,Annika Spottke,Alessio Squassina,Eystein Stordal,Juan Tartan,Lluís Tàrraga,Anbupalam Thalamuthu,Thomas Tegos,Giuseppe Tosto,Latchezar Traykov,Lucio Tremolizzo,André Uitterlinden,Abbe Ullgren,Sergi Valero,Otto Valladares,Christine Broeckhoven,Jeffery Vance,Badri Vardarajan,Aad Lugt,Jeroen Rooij,John Swieten,Jean‐Sébastien Vidal,Jonathan Vogelgsang,Martin Vyhnálek,Michael Wagner,David Wallon,Leonie Weinhold,Gill Livingston,Gill Windle,Mary Yannakoulia,Habil Zare,Xiaoling Zhang,Congcong Zhu,Miren Zulaica,Bruce Psaty,Jaap Goudsmit,María Serpente,Perminder Sachdev,Federica Piras,Valentina Ciullo,Jacob Shofany,Jakub Hort,Magda Tsolaki,Margaret Flanagan,Chiara Zoia,Maria Zompo,Patrizia Bastiani,Mari Takalo,Giacomina Rossi,Tiina Laatikainen,Jaakko Tuomilehto,Martin Ingelsson,Kristel Sleegers,Markku Peltonen,Richard Abraham,Christopher Shaw,Nicholas Bass,Agustı́n Ruiz,Alfredo Ramı́rez,Jean‐Charles Lambert,Pangiotis Deloukas,Amy Gerrish,Panos Deloukas,Denise Harold,Paul Hollingworth,Jarret Johnston,Lesley Jones,Brian Lawlor,Michelle Lupton,Aoibhinn Lynch,Stuart Pickering‐Brown,Michael O’Donovan,Peter Passmore,John Powell,Petroula Proitsi,Martin Rossor,Andrew McQuillin,Stephen Todd,Catherine Mummery,Natalie Ryan,Giordano Lacidogna,Ad Adarmes-Gómez,Ana Mauleón,Ana Pancho,A. Gailhajenet,Asunción Lafuente,Daniel Macías‐García,E. Martín,E. Pelejà,Fátima Carrillo,Isabel Merlín,L. Garrote-Espina,Liliana Vargas,Mario Ezquerra,M. Marín,Ma Labrador,Mar Buendía,M. Alonso,M. Guitart,Mariona Moreno,Marta Ibarria,M.Á. Espiñeira-Periñán,Núria Aguilera,Pilar Gómez‐Garre,R. Escuela,Rocío Pineda-Sánchez,R. Vigo-Ortega,Silvia Jesús,Silvia Preckler,Silvia Rodrigo‐Herrero,Susana Diego,Alessandro Vacca,Fausto Roveta,Nicola Salvadori,Elena Chipi,Henning Boecker,Christoph Laske,Robert Perneczky,Costas Anastasiou,Daniel Janowitz,Rainer Malik,Kayenat Parveen,Sara López‐García,Anna Antonell,Kalina Mihova,Diyana Belezhanska,Heike Weber,Silvia Kochen,Patricia Solís,Nancy Medel,Julieta Lisso,Zulma Sevillano,Daniel Politis,Valeria Cores,Carolina Cuesta,Juan Bacha,Mario Rios,Aldo Saenz,Dana Palacio,Ignacio Etchepareborda,Matias Köhler,Gisela Novack,Federico Prestia,Pablo Galeano,Eduardo Castaño,Sandra Germani,Matias Rojo,Carlos Ingino,Carlos Mangone,David Rubinsztein,Stefan Teipel,Nathalie Fiévet,Vincent Deramerourt,Charlotte Forsell,Andrea Arighi,Maria Bjerke,Ellen Roeck,Martin Heijer,Natividad Olivar,Olalla Maroñas,Raúl Núñez‐Llaves,Clàudia Olivé,Guillermo Amer-Ferrer,Martirio Antequera,J Burguera,M. Casajeros,Marian Pancorbo,S. Hevilla,M. Espinosa,Agustina Legaz,Salvadora Manzanares,Marta Marín‐Oto,Juan Marín-Muñoz,Tamara Marín,Begoña Martínez,Victoriana Martínez,Pablo Álvarez,Maite Mendióroz,María Periñán-Tocino,Diego Asúa,Silvia Rodrigo,I. Sastre,M.P. Vicente,L. Vivancos,Jacques Epelbaum,Didier Hannequin,M. Ikram,Peter Heutink,Éloi Magnin,Amy Williams,Charlene Thomas,Claire Davies,Will Nash,Kimberley Dowzell,Atahualpa Castillo-Morales,Mateus Bernardo-Harrington,James Turton,Jenny Lord,Emma Vardy,Elizabeth Fisher,Jason Warren,Rita Guerreiro,Thor Aspelund,Reinhard Heun,Mary Sano,Britta Schürmann,André Lacour,Christine Herold,Janet Johnston,Yogen Patel,Denis Evans,Tim Becker,Donald Warden,Gordon Wilcock,Robert Clarke,Yoav Ben‐Shlomo,Nigel Hooper,Honghuang Lin,Nicholas Warner,John Gallacher,Isabella Heuser,Thomas Cushion,Norman Klopp,Manuel Mayhaus,Sabrina Pinchler,Thomas Feulner,Carol Brayne,H.-Erich Wichmann,Shahram Bahrami,Ingunn Bosnes,Sverre Bergh,Aarno Palotie,Howard Jacob,Athena Matakidou,Adam Ziemann,Sally John,Robert Plenge,Christopher Brown,Michele Hu,Meg Ehm,Dawn Waterworth,Caroline Fox,Anders Hamsten,Kathy Klinger,Kathy Call,Timothy Behrens,Patrick Loerch,Tomi Mäkelä,Petri Virolainen,Kari Pulkki,Terhi Kilpi,Jukka Partanen,Anne Pitkäranta,Riitta Kaarteenaho,Seppo Vainio,Raisa Serpi,Tarja Laitinen,Johanna Mäkelä,Veli‐Matti Kosma,Outi Tuovila,Minna Hendolin,Raimo Pakkanen,Jeff Waring,Bridget Riley‐Gillis,Jiang Liu,Anne Lehtonen,Dorothée Diogo,Catherine Marshall,Xinli Hu,Matthias Gossel,Robert Graham,Beryl Cummings,Annika Auranen,Mikko Arvas,Jaakko Parkkinen,Reetta Hinttala,Johannes Kettunen,Minna Karjalainen,Jari Laukkanen,Valtteri Julkunen,Anne Remes,Reetta Kälviäinen,Jukka Peltola,Pentti Tienari,Juha Rinne,Jeffrey Waring,Sahar Esmaeeli,Nizar Smaoui,Susan Eaton,Sanni Lahdenperä,Janet Adelsberg,John Michon,Geoff Kerchner,Natalie Bowers,Edmond Teng,John Eicher,Vinay Mehta,Padhraig Gormley,Kari Linden,Christopher Whelan,Fanli Xu,Martti Färkkilâ,Sampsa Pikkarainen,Airi Jussila,Timo Blomster,Mikko Kiviniemi,Markku Voutilainen,Bob Georgantas,Graham Heap,Fedik Rahimov,Keith Usiskin,Tim Lu,Danny Oh,Jorge Gordillo,Melissa Miller,Linda McCarthy,Kari Eklund,Antti Palomäki,Pia Isomäki,Laura Pirilä,Oili Kaipiainen‐Seppänen,Johanna Huhtakangas,Apinya Lertratanakul,Marla Hochfeld,Nan Bing,Nina Mars,Margit Pelkonen,Paula Kauppi,Hannu Kankaanranta,Terttu Harju,David Close,Steven Greenberg,Hubert Chen,Jo Betts,Soumitra Ghosh,Ko Dijk,Teemu Niiranen,Markus Juonala,Kaj Metsärinne,Mika Kähönen,Juhani Junttila,Jussi Pihlajamäki,Juha Sinisalo,Marja‐Riitta Taskinen,Benjamin Challis,Andrew Peterson,Audrey Chu,Anthony Muslin,Heikki Joensuu,Tuomo Meretoja,Lauri Aaltonen,Johanna Mattson,Peeter Karihtala,Saila Kauppila,Päivi Auvinen,Klaus Elenius,Relja Popovic,Jennifer Schutzman,Andrey Loboda,Aparna Chhibber,Heli Lehtonen,Stefan McDonough,Marika Crohns,Diptee Kulkarni,Kai Kaarniranta,Joni Turunen,Terhi Ollila,Sanna Seitsonen,Giovanni Veronesi,Vesa Aaltonen,Hannele Uusitalo‐Järvinen,Marja Luodonpää,Nina Hautala,Stephanie Loomis,Erich Strauss,Hao Chen,Anna Podgornaia,Joshua Hoffman,Kaisa Tasanen,Laura Huilaja,Katariina Hannula-Jouppi,Teea Salmi,Sirkku Peltonen,Leena Koulu,Ilkka Harvima,Ying Wu,David Choy,Pirkko Pussinen,Aino Salminen,Tuula Salo,David Rice,Pekka Nieminen,Ulla Palotie,Maria Siponen,Liisa Suominen,Päivi Mäntylä,Ulvi Gürsoy,Vuokko Anttonen,Kirsi Sipilä,J. Davis,Danjuma Quarless,Slavé Petrovski,Eleonor Wigmore,Rion Pendergrass,Paola Bronson,Ellen Tsai,Yunfeng Huang,Joseph Maranville,Elmutaz Mohammed,Eiman Mohammed,Samir Wadhawan,Erika Kvikstad,Minal Çalışkan,Diana Chang,Tushar Bhangale,Sarah Pendergrass,Emily Holzinger,Xing Chen,Åsa Hedman,Karen King,Clarence Wang,Ethan Xu,Franck Augé,Clément Chatelain,Deepak Rajpal,Dongyu Liu,Katherine Call,Tai-he Xia,Matt Brauer,Mitja Kurki,Juha Karjalainen,Aki Havulinna,Anu Jalanko,Priit Palta,Pietro Parolo,Wei Zhou,Susanna Lemmelä,Manuel Rivas,Jarmo Harju,Arto Lehistö,Vincent Llorens,Hannele Laivuori,Sina Rüeger,Mari Niemi,Taru Tukiainen,Mary Reeve,Henrike Heyne,Kimmo Palin,Javier Garcia-Tabuenca,Harri Siirtola,Tuula Palotie,Jiwoo Lee,Kristin Tsuo,Kati Kristiansson,Kati Hyvärinen,Jarmo Ritari,Miika Koskinen,Katri Pylkäs,Marita Kalaoja,Tuomo Mantere,Eeva Kangasniemi,Sami Heikkinen,Eija Laakkonen,Csilla Sipeky,Samuel Heron,Antti Karlsson,Dhanaprakash Jambulingam,Venkat Rathinakannan,Risto Kajanne,Mervi Aavikko,Manuel Jiménez,Pietro Parola,Masahiro Kanai,Mari Kaunisto,Elina Kilpeläinen,Tuomo Kiiskinen,Georg Brein,Awaisa Ghazal,Anastasia Shcherban,Kati Donner,Anu Loukola,Päivi Laiho,Tuuli Sistonen,Essi Kaiharju,Markku Laukkanen,Elina Järvensivu,Sini Lähteenmäki,Lotta Männikkö,Regis Wong,Hannele Mattsson,Tero Hiekkalinna,Teemu Paajanen,Kalle Pärn,Javier Gracia‐Tabuenca,Erin Abner,Alyssa Aguirre,Marilyn Albert,Roger Albin,Mariet Allen,Lisa Alvarez,Liana Apostolova,Steven Arnold,Craig Atwood,Gayle Ayres,Thomas Obisesan,Robert Barber,Lisa Barnes,Thomas Beach,James Becker,Gary Beecham,Duane Beekly,Bruno Benítez,John Bertelson,Flanagan Margaret,Deborah Blacker,Bradley Boeve,James Burke,Jeffrey Burns,Joseph Buxbaum,Nigel Cairns,Christopher Carlson,José Brás,Scott Chasse,Marie‐Françoise Chesselet,Alessandra Chesi,Nathaniel Chin,Suzanne Craft,Paul Crane,David Cribbs,Elizabeth Crocco,Carlos Cruchaga,C. Cullum,Eveleen Darby,Bárbara Davis,Philip Jager,Charlie DeCarli,John DeToledo,Malcolm Dick,Melissa Murray,Beth Dombroski,Rachelle Doody,Ranjan Duara,Nilüfer Ertekin‐Taner,Thomas Fairchild,Markus Riemenschneider,Martin Farlow,John Farrell,Victoria Fernandez-Hernandez,Steven DeKosky,Matthew Frosch,Douglas Galasko,Adriana Gamboa,Marla Gearing,Daniel Geschwind,B. Ghetti,John Gilbert,Thomas Grabowski,Clifford Jack,Struan Grant,Robert Green,John Growdon,Hákon Hákonarson,James Hall,Ronald Hamilton,Oscar Harari,Lindy Harrell,Jacob Haut,Elizabeth Head,Victor Henderson,Michelle Hernandez,Timothy Hohman,Lawrence Honig,Ryan Huebinger,Matthew Huentelman,Christine Hulette,Bradley Hyman,Linda Hynan,Laura Ibáñez,Gail Jarvik,Suman Jayadev,Lee‐Way Jin,Kurt Johnson,Leigh Johnson,M. Kamboh,Anna Karydas,Mindy Katz,Jeffrey Kaye,C. Keene,Aisha Khaleeq,Ronald Kim,Janice Knebl,Neil Kowall,Joel Kramer,Frank LaFerla,James Lah,Eric Larson,Edward Lee,Alan Lerner,Yuk Leung,Allan Levey,Mingyao Li,Richard Lipton,Mark Logue,Rth Ho,John Malamon,Douglas Mains,Daniel Marson,Frank Martiniuk,Deborah Mash,Eliezer Masliah,Paul Massman,Arjun Masurkar,Wayne McCormick,Susan McCurry,Andrew McDavid,Ann McKee,Bruce Miller,Jesse Mez,Carol Miller,John Morris,Thomas Wingo,Jose‐Alberto Palma,Amanda Myers,Trung Nguyen,Sid O’Bryant,John Olichney,Marcia Ory,Raymond Palmer,Valory Pavlik,David Paydarfar,Victòria Pérez,Elaine Peskind,Ron Petersen,Jennifer Phillips‐Cremins,Wayne Poon,Marsha Polk,Huntington Potter,Liming Qu,Mary Quiceno,Joseph Quinn,Ashok Raj,Murray Raskind,Eric Reiman,‌Barry Reisberg,John Ringman,Erik Roberson,Monica Rodriguear,Ekaterina Rogaeva,Roger Rosenberg,Alexis Brice,Andrew Saykin,Julie Schneider,Lon Schneider,William Seeley,Susan Slifer,Scott Small,Amanda Smith,Janet Smith,Salvatore Spina,Peter George–Hyslop,Robert Stern,Alan Stevens,Stephen Strittmatter,David Sultzer,Russell Swerdlow,Rudolph Tanzi,Jeffrey Tilson,Juan Troncoso,Debby Tsuang,Annachiara Cagnin,Linda Eldik,Robert Vassar,Harry Vinters,Jean‐Paul Vonsattel,Sandra Weıntraub,Patrice Whitehead,Ellen Wijsman,Kirk Wilhelmsen,Benjamin Williams,Jennifer Williamson,Ralph Lucius,Thomas Wısnıewskı,Randall Woltjer,Martin Woon,Yasaman Saba,Chuang‐Kuo Wu,Chang‐En Yu,Lei Yu,Yuanchao Zhang,George Perry,Hieab Adams,Rufus Akinyemi,Muhammad Ali,Hugo Aparicio,Maryam Bahadori,Monique Breteler,Ganesh Chauhan,Hata Comic,Simon Cox,L. Cupples,Juho Wedenoja,Charles DeCarli,Marie-Gabrielle Duperron,Andrew Morris,Tavia Evans,Frank Fan,Alison Fohner,Beth Snitz,Mirjam Geerlings,Stephen Glatt,Héctor González,Monica Goss,Hans Grabe,Mohamad Habes,Mary Cushman,Edith Hofer,Elliot Hong,Timothy Hughes,Tiffany Kautz,Maria Knol,Paul Lacaze,Bhoom Suktitipat,Quentin Grand,Elizabeth Litkowski,Shuo Li,Dan Liu,Xuan Liu,Marisa Loitfelder,Alisa Manning,Pauline Maillard,Riccardo Marioni,Bernard Mazoyer,Debora Lent,Hao Mei,Aniket Mishra,Paul Nyquist,Jeffrey O’Connell,Yash Patel,Tomáš Paus,Zdenka Pausová,Katri Raikkonen-Talvitie,Moeen Riaz,Stephen Rich,Jerome Rotter,José Romero,Gena Roshchupkin,Muralidharan Sargurupremraj,Gaël Nicolas,Reinhold Schmidt,Jennifer Smith,Hema Sekhar,Reddy Rajula,Jean Shin,Jeannette Simino,Eeva Sliz,Alexander Teumer,Alvin Thomas,Adrienne Tin,Elliot Tucker‐Drob,Dina Vojinović,Yanbing Wang,Galit Weinstein,Dylan Williams,Katharina Wittfeld,Lisa Yanek,Yunju Yang,Lindsay Farrer,Towfique Raj,Karen Mather,Frank Jessen,Alexandre Mendonça,Margaret Pericak‐Vance,Philippe Amouyel,Julie Williams,Jordi Clarimón,Sudha Seshadri,Ole Andreassen,Cornelia Duijn,Rebecca Sims,Wiesje Flier,Sonia Moreno‐Grau,Rafael Campos-Martín,Manuel Serrano-Rı́os,Henry Paulson,Ángel Carracedo
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Apr 1, 2022
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