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Rescue of exhausted CD8 T cells by PD-1–targeted therapie... | ResearchHub

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Journal

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Cancer Oncology

DOI

10.1126/science.aaf0683

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Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

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Authors

Alice Kamphorst

Alice Kamphorst•Andreas Wieland•Rafi Ahmed

Published

March 9, 2017

Abstract

Immunotherapeutic PD-1–targeted therapies require CD28 to promote cancer cell killing.

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Journal

Topics

Cancer Oncology

DOI

10.1126/science.aaf0683