Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects.

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Journal

Genes & Development

Topics

Biology

Neuroscience

Developmental Neuroscience

Molecular Biology

Cellular And Molecular Neuroscience

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DOI

10.1101/gad.9.24.3136