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Iron-Overload–Related Disease inHFEHereditary Hemochromatosis
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Jan 16, 2008
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Abstract
Most persons who are homozygous for C282Y, the HFE allele most commonly asssociated with hereditary hemochromatosis, have elevated levels of serum ferritin and transferrin saturation. Diseases related to iron overload develop in some C282Y homozygotes, but the extent of the risk is controversial.
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