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Lopinavir–Ritonavir versus Nelfinavir for the Initial Treatment of HIV Infection
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Jun 27, 2002
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Abstract
Lopinavir is a newly developed inhibitor of human immunodeficiency virus (HIV) protease that, when formulated with ritonavir, yields mean trough plasma lopinavir concentrations that are at least 75 times as high as that needed to inhibit replication of wild-type HIV by 50 percent.
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