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Effects of Glucagon-Like Peptide 1 on Counterregulatory Hormone Responses, Cognitive Functions, and Insulin Secretion during Hyperinsulinemic, Stepped Hypoglycemic Clamp Experiments in Healthy Volunteers

Authors
Michael NauckMarkus HeimesaatWolff Schmiegel
Journal
The Journal of Clinical Endocrinology & Metabolism
Published
March 1, 2002

Abstract

Glucagon-like peptide 1 (GLP-1) and analogues are being evaluated as a new therapeutic principle for the treatment of type 2 diabetes. GLP-1 suppresses glucagon secretion, which could lead to disturbances of hypoglycemia counterregulation. This has, however, not been tested.

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Topics

DOI

10.1210/jcem.87.3.8355

License

Unknown License
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