Medical and Pediatric OncologyVolume 28, Issue 5 p. 342-347 HLH-94: A treatment protocol for hemophagocytic lymphohistiocytosis Jan-Inge Henter MD, PhD, Corresponding Author Jan-Inge Henter MD, PhD Department of Pediatrics, Karolinska Hospital, Stockholm, SwedenDepartment of Pediatrics, Karolinska Hospital, S-171 76 Stockholm, Sweden; fax +46-8 7293184, or the Histiocyte Society, 302 North Broadway, Pitman, NJ 08071, fax +1-609 589-6614, tel. +1-609 589-6606Search for more papers by this authorMaurizio Aricò MD, Maurizio Aricò MD Clinica Pediatrica, IRCCS Policlinico S. Matteo, Pavia, ItalySearch for more papers by this authorR. Maarten Egeler MD, PhD, R. Maarten Egeler MD, PhD Sophia Children's Hospital, Rotterdam, the NetherlandsSearch for more papers by this authorGöran Elinder MD, PhD, Göran Elinder MD, PhD Sachs' Children's Hospital, Stockholm, SwedenSearch for more papers by this authorBlaise E. Favara MD, Blaise E. Favara MD National Institutes of Health, Rocky Mountain Laboratory, Hamilton, MontanaSearch for more papers by this authorAlexandra H. Filipovich MD, Alexandra H. Filipovich MD Children's Hospital Medical Center, Cincinnati, OhioSearch for more papers by this authorHelmut Gadner MD, PhD, Helmut Gadner MD, PhD St. Anna Children's Hospital, Vienna, AustriaSearch for more papers by this authorShinsaku Imashuku MD, Shinsaku Imashuku MD Kyoto City Institute of Health and Environmental Sciences, JapanSearch for more papers by this authorGritta Janka-Schaub, Gritta Janka-Schaub Children's University Hospital, Hamburg, GermanySearch for more papers by this authorDiane Komp MD, Diane Komp MD Yale University School of Medicine, New Haven, ConnecticutSearch for more papers by this authorStephan Ladisch MD, Stephan Ladisch MD Center for Cancer and Transplantation Biology, Washington, DCSearch for more papers by this authorDavid Webb MD, David Webb MD Department of Hematology, Great Ormond Street Hospital, London, United KingdomSearch for more papers by this author Jan-Inge Henter MD, PhD, Corresponding Author Jan-Inge Henter MD, PhD Department of Pediatrics, Karolinska Hospital, Stockholm, SwedenDepartment of Pediatrics, Karolinska Hospital, S-171 76 Stockholm, Sweden; fax +46-8 7293184, or the Histiocyte Society, 302 North Broadway, Pitman, NJ 08071, fax +1-609 589-6614, tel. +1-609 589-6606Search for more papers by this authorMaurizio Aricò MD, Maurizio Aricò MD Clinica Pediatrica, IRCCS Policlinico S. Matteo, Pavia, ItalySearch for more papers by this authorR. Maarten Egeler MD, PhD, R. Maarten Egeler MD, PhD Sophia Children's Hospital, Rotterdam, the NetherlandsSearch for more papers by this authorGöran Elinder MD, PhD, Göran Elinder MD, PhD Sachs' Children's Hospital, Stockholm, SwedenSearch for more papers by this authorBlaise E. Favara MD, Blaise E. Favara MD National Institutes of Health, Rocky Mountain Laboratory, Hamilton, MontanaSearch for more papers by this authorAlexandra H. Filipovich MD, Alexandra H. Filipovich MD Children's Hospital Medical Center, Cincinnati, OhioSearch for more papers by this authorHelmut Gadner MD, PhD, Helmut Gadner MD, PhD St. Anna Children's Hospital, Vienna, AustriaSearch for more papers by this authorShinsaku Imashuku MD, Shinsaku Imashuku MD Kyoto City Institute of Health and Environmental Sciences, JapanSearch for more papers by this authorGritta Janka-Schaub, Gritta Janka-Schaub Children's University Hospital, Hamburg, GermanySearch for more papers by this authorDiane Komp MD, Diane Komp MD Yale University School of Medicine, New Haven, ConnecticutSearch for more papers by this authorStephan Ladisch MD, Stephan Ladisch MD Center for Cancer and Transplantation Biology, Washington, DCSearch for more papers by this authorDavid Webb MD, David Webb MD Department of Hematology, Great Ormond Street Hospital, London, United KingdomSearch for more papers by this author First published: 07 December 1998 https://doi.org/10.1002/(SICI)1096-911X(199705)28:5<342::AID-MPO3>3.0.CO;2-HCitations: 331AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Henter J-I, Söder O, Öst A, Elinder G: Incidence and clinical features of familial hemophagocytic lymphohistiocytosis in Sweden. Acta Paediatr Scand 80: 428– 35, 1991. 2 The Writing Group of the Histiocyte Society. Histiocytosis syndromes in children. Lancet i: 208– 209, 1987. 3 Henter JI, Elinder G, Öst Å, and the FHL Study Group of the Histiocyte Society. Diagnostic guidelines for hemophagocytic lymphohistiocytosis. Semin Oncol 18: 29– 33, 1991. 4 Risdall RJ, McKenna RW, Nesbit ME, Krivit W, Balfour HH Jr, Simmons RL, Brunning RD: Virus–associated hemophagocytic syndrome. A benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 44: 993– 1002, 1979. 5 Arico M, Janka G, Fischer A, Henter J-I, Blanche S, Elinder G, Martinetti M, Rusca MP, for the FHL Study Group of the Histiocyte Society. Hemophagocytic lymphohistiocytosis: Diagnosis, treatment, and prognostic factors. Report of 122 children from the international registry. 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