Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

Bijoy Menon,Raul Nogueira,Ryan McTaggart,Andrew Demchuk,Alexandre Poppe,Brian Buck,Olga Rukovets,Dar Dowlatshahi,Brian Adel,Richard Swartz,Ruchir Shah,Eric Sauvageau,Charlotte Zerna,Johanna Ospel,Manish Joshi,Mohammed Almekhlafi,Karla Ryckborst,Mark Boulos,Kathy Heard,David Garman,Diogo Haussen,Shawna Cutting,Shelagh Coutts,Daniel Roy,Jeremy Rempel,Axel Rohr,Daniela Iancu,Demetrios Sahlas,Amy Yu,Thomas Devlin,Ricardó Hanel,Volker Puetz,Frank Silver,Bruce Campbell,René Chapot,Jeanne Teitelbaum,Jennifer Mandzia,Timothy Kleinig,David Turkel‐Parrella,Donald Heck,Michael Kelly,Aditya Bharatha,Oh Bang,Ashutosh Jadhav,Rishi Gupta,Donald Frei,Jason Tarpley,Cameron McDougall,Staffan Holmin,Joung‐Ho Rha,Ajit Puri,Marie‐Christine Camden,Götz Thomalla,Hana Choe,Stephen Phillips,Ajay Malhotra,John Thornton,Simon Nagel,Ji Heo,Sung‐Il Sohn,Marios Psychogios,Ronald Budzik,Sidney Starkman,Coleman Martin,Paul Burns,Séan Murphy,George Lopez,Joey English,Michael Tymianski,Philip Barber,Eric Smith,Simerpreet Bal,Suresh Subramaniam,Steven Peters,Phillippe Couillard,Gary Klein,Peter Stys,John Norrie,Alim Mitha,Muneer Eesa,William Morrish,Saad Alqatani,Nima Kashani,Prasanna Venkatesan,Erika Teleg,Amith Sitaram,Brett Graham,Stephen Gaal,Aimen Moussaddy,Debabrata Chakraborty,Nicholas Maraj,Andrew Loockey,Shuo Chen,Ravinder Singh,Abdulaziz Sultan,R.M. Asuncion,Dominic Tse,Darshan Doshi,Ondřej Volný,Piyush Ojha,Ankur Wadhwa,Martha Marko,Nishita Singh,Sanchea Wasyliw,Carol Kenney,Supriya Save,Anitha Jambula,Nancy Newcommon,Gavin Hull,Darcy Blackstock,Sharon Kiszczak,L Zimmel,Michelle Wright,Cari Jahraus,Linda Andersen,Shelly Bohn,Joseph Paul,Odin Zhang,Craig Doram,Andrea Hanley,Lori Campbell,A.M. Ure,F Taylor,Dominic Hul,Samuel Wiebe,Marina Saluzzi,Nicole Blenkin,Richard Frayne,Kennedy Lees,Ashfaq Shuaib,Thomas Jeerakathil,Glen Jickling,Richard Owen,Robert Ashforth,Tom Yeo,Trevor Kotylak,Cian O’Kelly,Michael Chow,Muzaffer Siddiqui,Maher Saqqur,Atlantic D’Souza,Mar Lloret,Asif Butt,Ali Nomani,Hayrapet Kalashyan,Sibi Thirunavukkarasu,Juline Jabs,Paige Fairall,Lori Piquette,A. Green,Gord Gubitz,J Heidenreich,Thien Huynh,Jai Shankar,William Maloney,Robert Vandorpe,Matthias Schmidt,Gwynedd Pickett,Adrienne Weeks,Joseph Jarrett,Debbie MacDonald,Joanna Arsenault,Ruth Kinnear,Michael Mayich,Melfort Boulton,María Bullrich,Sebastián Fridman,Ruba Kiwan,Donald Lee,Stephen Lownie,Alexander Khaw,Sachin Pandey,Manas Sharma,Luciano Sposato,Kevin Wade,Beth Beauchamp,Lindsay Lambourn,Belinda Amato-Marziali,Nicole Daneault,Yan Deschaintre,Laura Gioia,Grégory Jacquin,Céline Odier,Christian Stapf,Jean Raymond,Alain Weill,Marlène Lapierre,Nadia Jadil,Judlène Jolteus,Mark Angle,Mathew Hannouche,Mohamed Badawy,Justin Létourneau,Maria Cortes,Grant Linnell,Donateela Tampieri,Lucy Vieira,Catherine Legault,Liam Durcan,Angela Moore,Erin Cole,Claire Magnussen,Kristiana Salmon,Salma Khalil,Mohamed El‐Sakhawy,Lindsay Waxman,Wynne Abdon,Sonia Lai,Michel Shamy,Grant Stotts,Dylan Blacquière,Howard Lesiuk,Aiman Quateen,Brian Drake,Brian Dewar,Zeinab Daham,Gary Hunter,Lissa Peeling,Ruth Whelan,Aaron Garner,Lilian Urroz,Sharleen Maley,Leanne Casaubon,Aleksandra Pikula,Martín Campo,Joanna Schaafsma,Cheryl Jaigobin,Timo Krings,Vítor Pereira,Ronit Agid,Richard Farb,Libby Kalman,Anne Cayley,Janice Williams,Tim Stewart,Karen Misquitta,Daniel Selchen,Thomas Marotta,Dipanka Sarma,Walter Montanera,Juluan Spears,Gustavo Saposnik,Pawel Kostyrko,Yangmei Li,Carmen Parra-Farina,Jose Diestro,Steve Verreault,Ariane Mackey,Marie‐Ève Audet,Geneviève Milot,Pascale Lavoie,Jean‐Luc Gariépy,Karine Collard,Annette Haché,Ahmed Alshanbari,Josephine Baldwin,Luciana Catanese,Bing Chen,Danielle Boasquevisque,Aviraj Deshmukh,Jordan Knapman,Shana Lamers,Ramiro Larrazabal,Susan Macmillan,Lauren Mai,Alicia Mattia,Sumiti Nayar,Kuan Ng,Wieslaw Oczkowski,Kanjana Perera,Mays Shawawrah,Ashkan Shoamanesh,Gita Sobhi,Nabeel Syed,Noran Taher,Cheyanne Vandervelde,D Pharm,Philip Teal,Oscar Benavente,Laura Wilson,Sharanpal Mann,Samuel Yip,Colleen Murphy,Manraj Heran,Fabio Settecase,Gary Redekop,Charles Haw,Genoveva Maclean,Karina Murray,Rosalin Chiu,Alana Flexman,Eilidh Strecha,Yolanda Gayton,Judy Yip,David Gladstone,Julia Hopyan,Houman Khosravani,Herbert Alzate,Alisia Southwell,Maneesha Kamra,Kaitlyn Lopes,Arunima Kapoor,Leodante Costa,Victor Yang,Erin Dyer,Brenda Knowles,Jennifer Nichols,Jennifer Patterson,Krista Cope,Lee Dickerson,Katrina Barton,Kimberly Gray,Ticey Massengale,Melanie Miller,Cindy Simpson,Sabrina Walker,Chlin Tennyson-Yemm,Richard Bellon,Benjamin Atchie,Ian Kaminsky,Duandelyn Wilson,Nicolle Schraeder,Eric Arias,Lisa Kodis,Mark Talley,Alex Edinger,Tiffany Talley,Ita Dempsey,Laurie Williams,Scott Williams,Sonny Kupniewski,Brad Fasbinder,Joanna Snead,Larami Mackenzie,D. Weisman,Osman Kozak,Qaisar Shah,Dan Gzesh,Kandan Kulandaivel,John Khoury,Brad Klein,Patricia Bussinger,Lisa Griffin,Ashley DePalmo,Cynthia Oliva,Tudor Jovin,Cynthia Kenmuir,Brian Jankowitz,Bradley Gross,Marcelo Rocha,Matthew Starr,Merritt Brown,Christine Hawkes,Kavit Shah,Danoushka Tememe,Gregory Walker,Pratit Patel,B Klein,Habibullah Ziayee,Kaustubh Limaye,Lisa Baxendell,Valerie Gilchrist,Patricia Feineigle,Kelsea Haibach,Cathy Every,Shashvat Desai,Maryam Zulfiqar,Linda Gibson‐Young,Sean Barrett,Karthikeyan Arcot,Steven DiCrescento,Jeffrey Farkas,Gregory Filipowski,Jennifer Frontera,Danielle Joset,Jeremy Liff,Erica Scher,Cheryl Kelly,Akshal Patel,Stephen Monteith,Kunakorn Atchaneeyasakul,Adrian Burgos,Janice Chua,Nathan Gaines,Ileana Grunberg,Judy Guzy,Zuolu Liu,Neil Maluste,Lucas Ramírez,L. Sharma,M Brown,Colin McDonald,Mateo Calderon,Mitch Hargis,Christina Roels,Prabhu Emmady,Talat Alvi,Mahesh Jayaraman,Wendy Smith,Susan Foley,G Paolucci,Richard Has,Katie Quinn,Lindsey Fuller,Rebecca Brierley,Christina Watkins,Nicole Demir,Alejandro Vargas,Nicholas Osteraas,Becky Holtz,Amin Aghaebrahim,Mohamad Chmayssani,Neeraj Naval,Jason Day,Scott Dellorso,Benjamin Ludwig,Derek Schemmel,Nancy Ebreo,Karen Bell,Lanai Lewis,Marjorie Delucia,Michael Frankel,Nirav Bhatt,Nicolas Bianchi,Aaron Anderson,Samir Belagaje,Bernardo Liberato,Srikant Rangaraju,Alhamza Al‐Bayati,Jonathan Grossberg,Leah Craft,Kiva Schindler,Erin Schaad,Meagan Schultz,Lorretta Southerly,Shannon Doppelheuer,Jacquelyn Charlton,Jason Faggard,Zuzana Barbret,Ethan Han,Robin Walters,Jaydevsinh Dolia,Sleiman El-Jamal,Brendan Eby,Yasir Saleem,Harrison Pearl,Kishan Patel,Haseeb Rahman,Reema Butt,Stephen English,M Howk,Jasmeet Singh,Francesco Massari,Katyucia Rodrigues,Anna Kühn,Nobl Barazangi,Nick Telischak,Warren Kim,Josh Ross,Nata DeVole,Jessica Redford,Milena Ferreira,Katie Ponting,Helen Shen,Ann Bedenk,Susila Patel,Julia Fernandess,Michael Ke,Ilanit Spokoyny,Billy Gao,David Tong,Xiaomeng Chen,Christine Wong,Jessica Choe,Debbie Summers,Christine Boutwell,Karin Olds,Suzanne Crandall,John Eatman,Naveed Akhtar,W Holloway,J Halpin,Brett Donegan,David Hwang,Emily Gilmore,Nils Petersen,Kevin Sheth,Stacy Brown,Rachel Beekman,Benjamin George,Firas Kaddouh,Guido Falcone,Charles Wira,Charles Matouk,Caitlin Loomis,Hardik Amin,Christoph Stretz,Reshma Narula,Adam Jasne,Lauren Sansing,Tijil Agarwal,Sara Jasak,Dominique Fontaine,Zachary King,Lindsey Kuohn,Hailey Orgass,Megan Leary,Joan Nye,Kelsey Halbert,Karin Nystrӧm,Kaile Neuschatz,Dawn Petrucci,Anna Coppola,Treasure Joyce,Sam Hou,Mark Umekubo,Catrice Nakamura,Renee Ovando,Diana Zúñiga,Yih Nien,Fernando Basto,Allison Arch,Laura Jong,William Conrad,Tara Abbott,Jay Yao,Scott Caganap,John Jordan,George Teitelbaum,Robert Darflinger,Mark Bain,Jennifer Czerniak,Katherine Groezinger,W. 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