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MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease
Authors
Pierre‐Antoine Juge,Joyce Lee
Esther Ebstein,Hiroshi Furukawa,Evgenia Dobrinskikh,Steven Gazal,Caroline Kannengiesser,Sébastien Ottaviani,Shomi Oka,Shigeto Tohma,Naoyuki Tsuchiya,Jorge Rojas‐Serrano,Montserrat González-Pérez,Mayra Mejía,Ivette Buendía-Roldán,Ramcés Falfán‐Valencia,Enrique Ambrocio-Ortiz,Effrosyni Manali,Spyros Papiris,T. Karageorgas,Dimitrios Boumpas,Katerina Antoniou,Coline Moorsel,Joanne Vis,Yaël Man,Jan Grutters,Yaping Wang,Raphaël Borie,Lidwine Wémeau-Stervinou,B. Wallaert,René‐Marc Flipo,Hilario Nunès,Dominique Valeyre,Nathalie Saidenberg-Kermanac’h,Marie‐Christophe Boissier,S. Marchand‐Adam,Aline Frazier,Pascal Richette,Yannick Allanore,Jean Sibilia,Claire Dromer,Christophe Richez,Thierry Schaeverbeke,H. Lioté,Gabriel Thabut,Nadia Nathan,Serge Amselem,Martin Soubrier,Vincent Cottin,Annick Clément,Kevin Deane,Avram Walts,Tasha Fingerlin,Aryeh Fischer,Jay Ryu,Eric Matteson,Timothy Niewold,Deborah Assayag,Andrew Gross,Paul Wolters,Marvin Schwarz,Michael Holers,Joshua Solomon,Tracy Doyle,Iván Rosas,Cornelis Blauwendraat,Mike Nalls,Marie‐Pierre Debray,Cathérine Boileau,Bruno Crestani,David Schwartz,Philippe Dieudé,Naoyuki Kamatani
+71 authors
,Κατερίνα ΑντωνίουPublished
Oct 20, 2018
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Abstract
Given the phenotypic similarities between rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) (hereafter, RA-ILD) and idiopathic pulmonary fibrosis, we hypothesized that the strongest risk factor for the development of idiopathic pulmonary fibrosis, the gain-of-function MUC5B promoter variant rs35705950, would also contribute to the risk of ILD among patients with RA.
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