Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function

Authors

Alexander Salter

Published

August 21, 2018

Abstract

How potently CAR T cells with CD28 or 4-1BB costimulatory domains stimulate intracellular signaling correlates with treatment efficacy.

Supporters

Support the authors with ResearchCoin

Journal

Science Signaling

Topics

DOI

10.1126/scisignal.aat6753

Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function

Authors

Alexander Salter

Published

August 21, 2018

Abstract

How potently CAR T cells with CD28 or 4-1BB costimulatory domains stimulate intracellular signaling correlates with treatment efficacy.

Supporters

Support the authors with ResearchCoin

Journal

Science Signaling

Topics

DOI

10.1126/scisignal.aat6753

Paper

Paper

Paper

Paper

Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function

Abstract

Supporters

Journal

Topics

DOI

Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function

Abstract

Supporters

Journal

Topics

DOI