Ser 1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations

Authors

Zejuan Sheng

Published

December 12, 2012

Abstract

LRRK2 autophosphorylation on Ser 1292 may be a useful indicator of kinase activity, providing a readout for screening candidate LRRK2 inhibitors.

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Support the authors with ResearchCoin

Journal

Science Translational Medicine

Topics

DOI

10.1126/scitranslmed.3004485

Ser 1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations

Authors

Zejuan Sheng

Published

December 12, 2012

Abstract

LRRK2 autophosphorylation on Ser 1292 may be a useful indicator of kinase activity, providing a readout for screening candidate LRRK2 inhibitors.

Supporters

Support the authors with ResearchCoin

Journal

Science Translational Medicine

Topics

DOI

10.1126/scitranslmed.3004485

Paper

Paper

Paper

Paper

Ser 1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations

Abstract

Supporters

Journal

Topics

DOI

Ser 1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations

Abstract

Supporters

Journal

Topics

DOI