Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents
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Authors
Marcin Wlodarski
Marcin Wlodarski•Shinsuke Hirabayashi•Charlotte Niemeyer
Published
December 24, 2015
Abstract
Key Points Germline GATA2 mutations account for 15% of advanced and 7% of all primary pediatric MDS and do not influence overall survival. The majority (72%) of adolescents with MDS and monosomy 7 carry an underlying GATA2 deficiency.
