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Fibulin-3 as a Blood and Effusion Biomarker for Pleural Mesothelioma

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Authors

Harvey Pass,Stephen Levin

Michael Harbut,Jonathan Melamed,Luis Chiriboga,Jessica Donington,Margaret Huflejt,Michele Carbone,David Chia,Lee Goodglick,Gary Goodman,Mark Thornquist,Geoffrey Liu,Marc Perrot,Ming‐Sound Tsao

+13 authors

,Chandra Goparaju

Journal

New England Journal of Medicine

Published

Oct 11, 2012

DOI

10.1056/nejmoa1115050

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Abstract

New biomarkers are needed to detect pleural mesothelioma at an earlier stage and to individualize treatment strategies. We investigated whether fibulin-3 in plasma and pleural effusions could meet sensitivity and specificity criteria for a robust biomarker.

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