TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Matthew Keuss,Sarah Hill,Matteo Zanovello,Weaverly Lee,Alexander Bampton,Flora Lee,Laura Masino,Yue Qi,Sam Bryce-Smith,Ariana Gatt,Martina Hallegger,Delphine Fagegaltier,Hemali Phatnani,Justin Kwan,Dhruv Sareen,James Broach,Zachary Simmons,Ximena Arcila-Londono,Edward Lee,Vivianna Deerlin,Neil Shneider,Ernest Fraenkel,Lyle Ostrow,Frank Baas,Noah Zaitlen,James Berry,Andrea Malaspina,Pietro Fratta,Gregory Cox,Leslie Thompson,Steven Finkbeiner,Efthimios Dardiotis,Timothy Miller,Siddharthan Chandran,Suvankar Pal,Eran Hornstein,Daniel MacGowan,Terry Heiman‐Patterson,Molly Hammell,Nikolaos Patsopoulos,Oleg Butovsky,Josh Dubnau,Avindra Nath,Robert Bowser,Matthew Harms,Eleonora Aronica,Mary Poss,Jennifer Phillips‐Cremins,John Crary,Nazem Atassi,Dale Lange,Darius Adams,Leonidas Stefanis,Marc Gotkine,Robert Baloh,Suma Babu,Towfique Raj,Sabrina Paganoni,Ophir Shalem,Colin Smith,Bin Zhang,Brent Harris,Iris Broce,Vivian Drory,John Ravits,Corey McMillan,Vilas Menon,Lani Wu,Steven Altschuler,Yossef Lerner,Rita Sattler,Kendall Keuren‐Jensen,Orit Rozenblatt–Rosen,Kerstin Lindblad‐Toh,Katharine Nicholson,Peter Gregersen,Jeong‐Ho Lee,Sulev Kokos,Stephen Muljo,Jia Newcombe,Emil Gustavsson,Sahba Seddighi,Joel Reyes,Steven Coon,Daniel Ramos,Giampietro Schiavo,Elizabeth Fisher,Maria Secrier,Tammaryn Lashley,Jernej Ule,Emanuele Buratti,Jack Humphrey,Michael Ward,Edward O’Neill