Abstract

Abstract. Alzheimers disease (AD) is a degenerative disease which was first discovered in 1907, it has been a far-reaching disease difficult to cure. Hundreds of millions of people have been plaguing AD. The high incidence rate and high death rate of AD has brought tremendous burden to country and society. Human has made significant achievement in pathobiology so far. This article first makes a brief introduction about the history of AD, and the clinical presentation of AD patients. Besides that, some issues may be neglected. Hypotheses about the pathogenicity and new treatment policy of AD have been mentioned in this essay, providing effective remedy of AD, such as primary neuropathologic criteria, amyloid positron emission tomography imaging and targeted therapies. This thesis introduces AD by doing a literature review anlysis. The critical essay summarizes the main body of academic papers, evaluates academic articles in specific fields. But it may also face the problem of what to discuss in a literature review.