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Plasma pTau217 ratio predicts continuous regional brain tau accumulation in amyloid‐positive early Alzheimer's disease

Internal Medicine

Cognitive Neuroscience

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Authors

Viswanath Devanarayan,Arnaud Charil

Kanta Horie,T. Doherty,Daniel Llano,Erica Andreozzi,Perminder Sachdev,Yuanqing Ye,Leema Murali,Jin Zhou,Larisa Reyderman,Harald Hampel,Lynn Kramer,Shobha Dhadda

+12 authors

,Michael Irizarry

Journal

Alzheimer s & Dementia

Published

Nov 22, 2024

DOI

10.1002/alz.14411

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Abstract

This study examines whether phosphorylated plasma Tau217 ratio (pTau217R) can predict tau accumulation in different brain regions, as measured by positron emission tomography (PET) standardized uptake value ratio (SUVR), for staging Alzheimer's disease (AD).

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