Abstract

Motivation: GRE based neuromelanin (NM) imaging at 7T is sensitive to B0 field disturbance by patient breathing or even mild head motion. Goal(s): A reduced FOV method is proposed for 7T NM imaging using 3D GRE with three saturation bands for creating MT contrast and reducing ghosting artifacts. Approach: The sequence has bilateral sagittal saturation bands placed in close proximity to the SNc for artifacts and FOV reduction, and the 3rd axial saturation band placed below the SNc for arterial blood suppression. Results: The method yields higher resolution, enhanced NM contrast, and a reduction in artifacts. Impact: The reduced FOV neuromelanin (NM) imaging method using three saturation bands offers higher resolution NM imaging at 7T with improved NM contrast and image quality.