Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Fanny Ip,Yuanbing Jiang,Han Cao,Ge Lv,Huan Zhong,Jiahang Chen,Ye Tao,Yuewen Chen,Yulin Zhang,Shuangshuang Ma,Ronnie Lo,Estella Tong,Michael Weiner,Paul Aisen,Ronald Petersen,Clifford Jack,William Jagust,John Trojanowski,Arthur Toga,Laurel Beckett,Robert Green,Andrew Saykin,John Morris,Leslie Shaw,Zaven Khachaturian,Greg Sorensen,Lew Kuller,Marcus Raichle,Steven Paul,Peter Davies,Howard Fillit,Franz Hefti,Wei Ma,Marek Mesulam,William Potter,Peter Snyder,Adam Schwartz,Tom Montine,Ronald Thomas,Michael Donohue,Sarah Walter,Devon Gessert,Tamie Sather,Gus Jiminez,Danielle Harvey,Matt Bernstein,Paul Thompson,Norbert Schuff,Bret Borowski,Jeff Gunter,Matthew Senjem,Prashanthi Vemuri,David Jones,Kejal Kantarci,Chad Ward,Robert Koeppe,Norm Foster,Eric Reiman,Kewei Chen,Chester Mathis,Susan Landau,Nigel Cairns,Erin Householder,Lisa Taylor‐Reinwald,Virginia Lee,Magdalena Korecka,Michal Figurski,Karen Crawford,Scott Neu,Tatiana Foroud,Steven Potkin,Li Shen,Kelley Faber,Sungeun Kim,Kwangsik Nho,Leon Thal,Neil Buckholtz,Marylyn Albert,Richard Frank,John Hsiao,Jeffrey Kaye,Joseph Quinn,Betty Lind,Raina Carter,Sara Dolen,Lon Schneider,Sonia Pawluczyk,Mauricio Beccera,Liberty Teodoro,Bryan Spann,James Brewer,Helen Vanderswag,Adam Fleisher,Judith Heidebrink,Joanne Lord,Sara Mason,Colleen Albers,David Knopman,Kris Johnson,Rachelle Doody,Javier Villanueva-Meyer,Munir Chowdhury,Susan Rountree,Mimi Dang,Yaakov Stern,Lawrence Honig,Karen Bell,Beau Ances,Maria Carroll,Sue Leon,Mark Mintun,Stacy Schneider,Angela Oliver,Daniel Marson,Randall Griffith,David Clark,David Geldmacher,John Brockington,Erik Roberson,Hillel Grossman,Effie Mitsis,Leyla Toledo‐Morrell,Raj Shah,Ranjan Duara,Daniel Varón,Maria Greig,Peggy Roberts,Chiadi Onyike,Daniel D’Agostino,Stephanie Kielb,James Galvin,Brittany Cerbone,Christina Michel,Henry Rusinek,Mony Leon,Lidia Glodzik,Susan Santi,P. Doraiswamy,Jeffrey Petrella,Terence Wong,Steven Arnold,Jason Karlawish,David Wolk,Charles Smith,Gregory Jicha,P. Hardy,Partha Sinha,Elizabeth Oates,Gary Conrad,Oscar López,MaryAnn Oakley,Donna Simpson,Anton Porsteinsson,Bonnie Goldstein,Kim Martin,Kelly Makino,M. Ismail,Connie Brand,Ruth Mulnard,Gaby Thai,Catherine Mc-Adams-Ortiz,Kyle Womack,Dana Mathews,Mary Quiceno,Ramon Diaz‐Arrastia,Richard King,Myron Weiner,Kristen Martin-Cook,Michael Devous,Allan Levey,James Lah,Janet Cellar,Jeffrey Burns,Heather Anderson,Russell Swerdlow,Liana Apostolova,Kathleen Tingus,Ellen Woo,Daniel Silverman,Po Lu,George Bartzokis,Neill Graff‐Radford,Francine Parfitt,Tracy Kendall,Heather Johnson,Martin Farlow,Ann Hake,Brandy Matthews,Scott Herring,Cynthia Hunt,Christopher Dyck,Richard Carson,Martha MacAvoy,Howard Chertkow,Howard Bergman,Chris Hosein,Ging‐Yuek Hsiung,Howard Feldman,Benita Mudge,Michele Assaly,Charles Bernick,Donna Munic,Andrew Kertesz,John Rogers,Dick Trost,Diana Kerwin,Kristine Lipowski,Chuang‐Kuo Wu,Nancy Johnson,Carl Sadowsky,Walter Martínez,Teresa Villena,Raymond Turner,Kathleen Johnson,Brigid Reynolds,Reisa Sperling,Keith Johnson,Gad Marshall,Meghan Frey,Barton Lane,Allyson Rosen,Jared Tinklenberg,Marwan Sabbagh,Christine Belden,Sandra Jacobson,Sherye Sirrel,Neil Kowall,Ronald Killiany,Andrew Budson,Alexander Norbash,Patricia Johnson,Joanne Allard,Alan Lerner,Paula Ogrocki,Leon Hudson,Evan Fletcher,Owen Carmichael,John Olichney,Charles DeCarli,Smita Kittur,Michael Borrie,T‐Y Lee,Robert Bartha,Sterling Johnson,Sanjay Asthana,Cynthia Carlsson,Adrian Preda,Dana Nguyen,Pierre Tariot,Stephanie Reeder,Vernice Bates,Horacio Capote,Michelle Rainka,Douglas Scharre,Maria Kataki,Anahita Adeli,Earl Zimmerman,Dzintra Celmins,Alice Brown,Godfrey Pearlson,Karen Blank,Karen Anderson,Robert Santulli,Tamar Kitzmiller,Eben Schwartz,Kaycee Sink,Jeff Williamson,Pradeep Garg,Franklin Watkins,Brian Ott,Henry Querfurth,Geoffrey Tremont,Stephen Salloway,Paul Malloy,Stephen Correia,Howard Rosen,Bruce Miller,Jacobo Mintzer,Kenneth Spicer,David Bachman,Stephen Pasternak,Irina Rachinsky,Dick Drost,Nunzio Pomara,Raymundo Hernando,Antero Sarrael,Susan Schultz,Laura Ponto,Hyungsub Shim,Karen Smith,Norman Relkin,Gloria Chaing,Lisa Raudin,Amanda Smith,Kristin Fargher,Balebail Raj,Thomas Neylan,Jordan Grafman,Melissa Davis,Rosemary Morrison,Jacqueline Hayes,Shannon Finley,Karl Friedl,Debra Fleischman,Konstantinos Arfanakis,Olga James,Dino Massoglia,J. Fruehling,Sandra Harding,Elaine Peskind,Eric Petrie,Gail Li,Jerome Yesavage,Joy Taylor,Ansgar Furst,Vincent Mok,Timothy Kwok,Qihao Guo,Kin Mok,Maryam Shoai,John Hardy,Lei Chen,Amy Fu,Nancy Ip,Wei Wang