Abstract

Motivation: The habenula is evolutionarily conserved brain region which play a crucial role in sleep regulationGoal(s): To analysis the structural and functional relationship between habenula and individual sleep by 5T ultrahigh-resolution MRIApproach: Using ultrahigh-resolution structural and functional MRI, we parcellated lateral and medial portions of the habenula and calculated structural and functional connectivity on the basis of these parcellationsResults: We parcellated lateral and medial portions of the habenula and identified connectivity with salience, limbic and part of somatomotor networks, which led to the loss in average sleep and cognitive processesImpact: For the first time we identified the correlation between habenula and individual sleep using 5T ultrahigh-resolution MRI. By analyzing 300 samples high -resolution data, we revealed the neurological basis of individual sleep regulation, and provided new opinions for the mechanism of sleep diseases.