Motivation: Current diffusion readout methods have a relatively long echo time and readout duration, which prevent multi-echo imaging. Goal(s): To implement a diffusion sequence with multiple echoes readout for performing diffusion relaxometry. Approach: A 3-echo diffusion sequence, SPIDER, with variable density spiral readout was designed. Results: The proposed SPIDER showed comparable images with reference EPI method at shorter echo time. Impact: The proposed method showed the ability to acquire 3 echoes for 1mm2 resolution for low b-value, which could help multi-echo diffusion modeling.
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