Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes

Mark D. Chaffin,Dajiang J. Liu,Minxian X. Wang,Carlos A. Aguilar-Salinas,Lucinda Antonacci-Fulton,Diego Ardissino,Donna K. Arnett,Stella Aslibekyan,Gil Atzmon,Christie M. Ballantyne,Francisco Barajas-Olmos,Nir Barzilai,Lewis C. Becker,Lawrence F. Bielak,Joshua C. Bis,John Blangero,Eric Boerwinkle,Lori L. Bonnycastle,Erwin Bottinger,Donald W. Bowden,Matthew J. Bown,Jennifer A. Brody,Jai G. Broome,Noel P. Burtt,Brian E. Cade,Federico Centeno-Cruz,Edmund Chan,Yi-Cheng Chang,Yii-Der I. Chen,Ching-Yu Cheng,Won Jung Choi,Rajiv Chowdhury,Cecilia Contreras-Cubas,Emilio J. Cordova,Adolfo Correa,L Adrienne Cupples,Joanne E. Curran,John Danesh,Paul S. de Vries,Ralph A. DeFronzo,Harsha Doddapaneni,Ravindranath Duggirala,Susan K. Dutcher,Patrick T. Ellinor,Leslie S. Emery,Jose C. Florez,Myriam Fornage,Barry I. Freedman,Valentin Fuster,Ma. Eugenia Garay-Sevilla,Humberto Garcia-Ortiz,Soren Germer,Richard A. Gibbs,Christian Gieger,Benjamin Glaser,Clicerio Gonzalez,Maria Elena Gonzalez-Villalpando,Mariaelisa Graff,Sarah E Graham,Niels Grarup,Leif C. Groop,Xiuqing Guo,Namrata Gupta,Sohee Han,Craig L. Hanis,Torben Hansen,Jiang He,Nancy L. Heard-Costa,Yi-Jen Hung,Mi Yeong Hwang,Marguerite R. Irvin,Sergio Islas-Andrade,Gail P. Jarvik,Hyun Min Kang,Sharon L.R. Kardia,Tanika Kelly,Eimear E. Kenny,Alyna T. Khan,Bong-Jo Kim,Ryan W. Kim,Young Jin Kim,Heikki A. Koistinen,Charles Kooperberg,Johanna Kuusisto,Soo Heon Kwak,Markku Laakso,Leslie A. Lange,Jiwon Lee,Juyoung Lee,Seonwook Lee,Donna M. Lehman,Rozenn N. Lemaitre,Allan Linneberg,Jianjun Liu,Ruth J.F. Loos,Steven A. Lubitz,Valeriya Lyssenko,Ronald C.W. Ma,Lisa Warsinger Martin,Angelica Martinez-Hernandez,Rasika A. Mathias,Stephen T. McGarvey,Ruth McPherson,James B. Meigs,Thomas Meitinger,Olle Melander,Elvia Mendoza-Caamal,Ginger A. Metcalf,Xuenan Mi,Karen L. Mohlke,May E. Montasser,Jee-Young Moon,Hortensia Moreno-Macias,Alanna C. Morrison,Donna M. Muzny,Sarah C. Nelson,Peter M. Nilsson,Jeffrey R. O'Connell,Marju Orho-Melander,Lorena Orozco,Colin N.A. Palmer,Nicholette D. Palmer,Cheol Joo Park,Kyong Soo Park,Oluf Pedersen,Juan M. Peralta,Patricia A. Peyser,Wendy S. Post,Michael Preuss,Bruce M. Psaty,Qibin Qi,DC Rao,Susan Redline,Alexander P. Reiner,Cristina Revilla-Monsalve,Stephen S. Rich,Nilesh Samani,Heribert Schunkert,Claudia Schurmann,Daekwan Seo,Jeong-Sun Seo,Xueling Sim,Rob Sladek,Kerrin S. Small,Wing Yee So,Adrienne M. Stilp,S. Margaret Sunitha,E Shyong Tai,Claudia H.T. Tam,Kent D. Taylor,Yik Ying Teo,Farook Thameem,Brian Tomlinson,Michael Y. Tsai,Tiinamaija Tuomi,Jaakko Tuomilehto,Teresa Tusie-Luna,Rob M. van Dam,Ramachandran S. Vasan,Karine A. Viaud-Martinez,Fei Fei Wang,Xuzhi Wang,Hugh Watkins,Daniel E. Weeks,James G. Wilson,Daniel R. Witte,Tien-Yin Wong,Lisa R. Yanek,Sekar Kathiresan,Jerome I. Rotter,Michael Boehnke,Mark I. McCarthy,Cristen J. Willer,Pradeep Natarajan,Jason A. Flannick,Amit V. Khera,Gina M. Peloso,Mark Chaffin,Dajiang Liu,Minxian Wang,Margaret Selvaraj,David Zhang,Joseph Park,Carlos Aguilar‐Salinas,Donna Arnett,Christie Ballantyne,Francisco Barajas‐Olmos,Lewis Becker,Lawrence Bielak,Joshua Bis,Lori Bonnycastle,Erwin Böttinger,Donald Bowden,Matthew Bown,Jennifer Brody,Jai Broome,Noël Burtt,Brian Cade,Yi‐Cheng Chang,Yii‐Der Chen,Won Choi,Emilio Córdova,L. Cupples,Joanne Curran,Paul Vries,Ralph DeFronzo,Susan Dutcher,Patrick Ellinor,Leslie Emery,José Florez,Barry Freedman,Valentín Fuster,Ma. Garay‐Sevilla,Humberto Garcia‐Ortíz,Søren Germer,Richard Gibbs,Benjamin Gläser,Clicerio González,María González-Villalpando,Sarah Graham,Leif Groop,Craig Hanis,Nancy Heard‐Costa,Yi‐Jen Hung,Mi Hwang,Marguerite Irvin,Sergio Islas‐Andrade,Gail Jarvik,Hyun Kang,Sharon Kardia,Eimear Kenny,Alyna Khan,Bong‐Jo Kim,Ryan Kim,Young Kim,Heikki Koistinen,Soo Kwak,Leslie Lange,Donna Lehman,Rozenn Lemaître,Jianjun Li,Ruth Loos,Steven Lubitz,Rong Ma,Lisa Martin,Angélica Martínez‐Hernández,Rasika Mathias,Stephen McGarvey,James Meigs,Elvia Mendoza‐Caamal,Ginger Metcalf,Karen Mohlke,May Montasser,Hortensia Moreno-Macías,Alanna Morrison,Donna Muzny,Sarah Nelson,Peter Nilsson,Jeffrey O’Connell,Marju Orho‐Melander,Colin Palmer,Nicholette Palmer,Cheol Park,Kyong Park,Juan Peralta,Patricia Peyser,Wendy Post,Bruce Psaty,D. Rao,Alexander Reiner,Cristina Rodríguez‐Padilla,Stephen Rich,Jeong‐Sun Seo,Kerrin Small,Wing So,Adrienne Stilp,E Tai,Claudia Tam,Kent Taylor,Yik Teo,Michael Tsai,Teresa Tusié‐Luna,Rob Dam,Ramachandran Vasan,Karine Martinez,Feifei Wang,Daniel Weeks,James Wilson,Daniel Witte,Tien‐Yin Wong,Lisa Yanek,Daniel Rader,Jerome Rotter,Mark McCarthy,Cristen Willer,Jason Flannick,Amit Khera