Motivation: Ovarian cystic and predominantly cystic lesions are common tumor-like formations within the ovaries, necessitating precise diagnosis and differential analysis for effective clinical management. Goal(s): This study examines the effectiveness of amide proton transfer-weighted (APTw) MRI in differentiating cystic or predominately cystic ovarian lesions. Approach: 49 patients with ovarian lesions were prospectively scanned by APTw before surgery, and 20 volunteers were also scanned by APTw as a control group. Results: The results demonstrate APTw MRI's substantial value in identifying and distinguishing common ovarian cystic and predominantly cystic lesions, offering enhanced diagnostic precision in ovarian pathology. Impact: MR diagnostic techniques for ovarian lesions, including DWI and DCE-MRI, have their limitations. A timely diagnosis is crucial for improving patient prognosis. APTw imaging has shown research progress across various systems, yet its application in ovarian studies remains limited.
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