Abstract

Motivation: Long acquisition times have hindered many quantitative magnetic resonance imaging methods. Goal(s): In order to reduce the collection time, we propose a rapid and quantitative method for multi-parameter quantification. Approach: Multiple overlapping echo detachment (MOLED) imaging can enable multiparametric quantitative mapping for a single slice in just hundreds of milliseconds. To achieve simultaneous quantitative imaging of M0, T1, T2, T2*, B1, and ΔB0, we proposed the SSFP-MOLED method. Results: The results of both phantom and vivo experiments on a 3T whole-body scanner demonstrate that our method can accurately quantify multiple parameters, indicating promising clinical applications. Impact: We present a novel and efficient mapping method for multiparametric MRI (M0, T1, T2, T2*, B1, and ΔB0). This method not only enhances the efficiency of data collection for clinicians but also improves the diagnostic reliability of multi-center hospitals.