Abstract

Motivation: To investigate the potential of different CMR parameters as non-invasive, indirect indicators of NT-proBNP levels in HEpEF patients and to assess their utility in enhancing disease prognosis and assessment. Goal(s): The objective of this study is to explore the relationship between NT-proBNP and left ventricular functional parameters, T1 mapping, ECV, and myocardial strain parameters in CMR. Approach: A retrospective study was conducted with a cohort of HEpEF patients. Advanced cardiac MRI techniques were utilized to ascertain each CMR parameter. Results: A notable correlation was discerned between myocardial stress parameters and Native T1 values with serum NT-proBNP levels. Impact: NT-proBNP is a fundamental biomarker for assessing and predicting alterations in left ventricular function. Myocardial stress parameters and Native T1 showcase potential as non-invasive indicators.Future research must focus on multi-center, prospective studies to validate and expand on these findings.