Abstract

Titanium alloys are commonly used for bone grafting, but in mandibular defect repair, implantation possibly fails due to bacterial infection. The establishment of a long-acting drug delivery system through microspheres and titanium channels can reduce the risk of infection. However, there is insufficient research on the mechanism of microsphere attachment and microsphere-liquid two-phase flow in the hydroxyl-functionalized titanium implantation channel modified by a vacuum-drying-assisted laser texturing. In this paper, poly(lactic-