Abstract

Anorexia nervosa (AN) is a psychiatric illness with high mortality rates and limited treatment outcomes. Psilocybin treatment (PT) has shown promise for various mental health indications and there is significant interest in exploring its potential for AN; however, studies to date are preliminary. Given the probable surge in psychedelic studies for AN, more information is needed to understand how to successfully apply and optimize these treatments for this vulnerable population. In this Emerging Topics article, we present a nuanced exploration of the potential benefits and constraints of PT for AN, contextualized within the framework of our clinical findings from a modest phase 1 pilot study. We offer here a synthesis of first-hand experiences and comprehensive thematic insights gleaned from 10 individuals with lived experience, providing a rich tapestry of perspectives on this novel therapeutic approach.