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Islet-reactive CD8 + T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors
Authors
Slobodan Čulina,Ana Lalanne
Georgia Afonso,Karen Cerosaletti,Sheena Pinto,Guido Sebastiani,Klaudia Kuranda,Laura Nigi,Anne Eugster,Thomas Østerbye,Alicia Maugein,James McLaren,Kristin Ladell,Étienne Larger,Jean-Paul Beressi,Anna Lissina,Victor Appay,Howard Davidson,Søren Buus,David Price,Matthias Kühn,Ezio Bonifacio,Manuela Battaglia,Sophie Caillat‐Zucman,Francesco Dotta,Raphaël Scharfmann,Bruno Kyewski,Roberto Mallone,Jean‐Claude Carel,Nadia Tubiana‐Rufi,Lætitia Martinerie,Amélie Poidvin,Évelyne Jacqz-Aigrain,Laurence Corvez,Véronique Berruer,Jean‐François Gautier,Baz Baz,Nassima Haddadi,Fabrizio Andréelli,Chloé Amouyal,Sophie Jaqueminet,Olivier Bourron,Eric Dasque,Agnès Hartemann,Amal Lemoine-Yazigi,Danièle Dubois‐Laforgue,F. Travert,Marilyne Feron,Patrice Rolland,Valérie Vignali,Michel Marre,Philippe Chanson,Claire Briet,Pierre-Jean Guillausseau,Leila Ait-Bachir,Carole Collet,Frédéric Beziaud,V. Desforges-Bullet,Gwenaelle Petit-Aubert,Sophie Christin‐Maître,Bruno Fève,Camille Vatier,Nathalie Bourcigaux,Céline Lautridou,Najiba Lahlou,Prissile Bakouboula,Caroline Elie,Hélène Morel,Jean‐Marc Tréluyer,Marie‐Claude Gagnerault,Claire Maillard,Anna Jones
+70 authors
,Jacques EpelbaumJournal
Published
Feb 8, 2018
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Abstract
Islet-reactive CD8 + T cells are common in the periphery, but home to the pancreas preferentially in the context of type 1 diabetes.
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