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Feedback Suppression of PI3Kα Signaling in PTEN-Mutated Tumors Is Relieved by Selective Inhibition of PI3Kβ
Genetics
Molecular Biology
Cell Biology
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Authors
Sarit Schwartz
,
John Wongvipat
Cath Trigwell
,
Urs Hancox
,
Brett Carver
,
Vanessa Rodrik-Outmezguine
,
Marie Will
,
Paige Yellen
,
Elisa Stanchina
,
José Baselga
,
Howard Scher
,
Simon Barry
,
Charles Sawyers
,
Sarat Chandarlapaty
+12 authors
,
Neal Rosen
Journal
Cancer Cell
Published
Dec 24, 2014
DOI
10.1016/j.ccell.2014.11.008
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