Discovery and Optimization of Dihydroquinolin-2(1H)-ones as Novel Highly Selective and Orally Bioavailable Phosphodiesterase 5 Inhibitors for the Treatment of Pulmonary Arterial Hypertension

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Journal

Journal of Medicinal Chemistry

Topics

Chemistry

Biochemistry

Medicine

Internal Medicine

Pulmonary And Respiratory Medicine

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DOI

10.1021/acs.jmedchem.4c02123