Abstract TUPI (Timepix4-based Ultra-fast Photon Imaging) is the new family of direct conversion and vacuum-compatible hybrid detectors under design at Sirius, the Brazilian 4th generation light source. Based on the Timepix4 Application Specific Integrated Circuit (ASIC), it targets different kinds of experiments, such as tomography and spectrometry, and will be used in multiple bioimaging beamlines of Orion, Brazil's Biosafety Level 4 (BSL4) Laboratory project. Also, it will cover a wide energy range (5 to 45 keV) by using different sensors materials (Si, GaAs, CdTe, etc.). Designed in a modular approach to ensure scalability for constructing larger active areas in a compact form, each TUPI module will be composed by a set of 3x side-by-side Timepix4 ASICs to provide a sensitive area of approximately 74×28 mm 2 (1344×512 pixels of 55 μm pitch), streaming up to 44 kfps through up to 48×10.24 Gbps optical links directly connected to a Data Acquisition (DAQ) system.

Conceptual design of TUPI (Timepix4-based Ultra-fast Photon Imaging) detector's hardware