Preschool depression and conduct disorder were stronger risk factors for developing full DSM-5 criteria for major depression in later childhood and early adolescence than well-established risk factors such as maternal history of depression or traumatic life events. Early interventions for preschool depression and conduct disorder could help young children at uniquely high risk for later major depression.

Trajectories of Preschool Disorders to Full DSM Depression at School Age and Early Adolescence: Continuity of Preschool Depression