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GOLM1 promotes cholesterol gallstone formation via ABCG5-... | ResearchHub

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GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers

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Authors

Yitong Li

Yitong Li•Weiqing Shao•Jinhong Chen

Published

December 10, 2024

Abstract

Metabolic dysfunction-associated steatohepatitis (MASH) is a significant risk factor for gallstone formation, but mechanisms underlying MASH-related gallstone formation remain unclear. Golgi membrane protein 1 (GOLM1) participates in hepatic cholesterol metabolism and is upregulated in MASH. Here, we aimed to explore the role of GOLM1 in MASH-related gallstone formation.

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Journal

Clinical and Molecular Hepatology

Topics

Internal Medicine

DOI

10.3350/cmh.2024.0657

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Supporters

Support the authors with ResearchCoin

Journal

Clinical and Molecular Hepatology

Topics

Internal Medicine

DOI

10.3350/cmh.2024.0657

License