Does STN-DBS in Parkinson's Disease affect cognition? A case-control neuropsychological study and clinical considerations

Abstract

Highlights•First study comparing PD-DBS patients to totally matched PD patients on pharmacologically therapy;•STN-DBS might worsen long-term memory, executive functions, and visuospatial abilities;•Cognitive profile before surgery contributed to clinical outcomes;•Guidelines for cognitive evaluation of PD patients for DBS surgery are needed.