Background: Coccidiosis is a serious parasitic disease caused by protozoan parasites of the genus Eimeria, presents an important risk to rabbits’ health and production. Methods: Potential bioactive compounds in the extract were identified by FT-IR analysis and the total content of phenolics, tannins and flavonoids was calculated. In addition, enzyme inhibitory and antioxidant effects were investigated. Result: The phytochemical results of methanolic extract of the leaves of R. nervosus showed the presence of 14 compounds of active chemical constituents. In addition, the results showed that the methanolic extract had the amount of TPC (54.33±0.198 mg/g DW), TFC (21.51±0.155 mg/g DW) and TTC (29.37±1.43 mg/g DW). The sporulation inhibition rate between 72- and 96-hour exposures, as the rate rose significantly with an increasing incubation period (p less than 0.05). The extract has inhibitory abilities on tested enzymes á-amylase and-glucosidase.
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