Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Xiangrui Meng,Swapnil Awasthi,Brett Adey,Karmel Choi,V. Chundru,Jonathan Coleman,Bart Ferwerda,Jerome Foo,Zachary Gerring,Olga Giannakopoulou,Priya Gupta,Alisha Hall,Arvid Harder,David Howard,Christopher Hübel,Alex Kwong,Daniel Levey,Brittany Mitchell,Guiyan Ni,Vanessa Ota,Oliver Pain,Gita Pathak,Eva Schulte,Xueyi Shen,Jackson Thorp,Alicia Walker,Shuyang Yao,Jian Zeng,Johan Zvrskovec,Dag Aarsland,Ky’Era Actkins,Mazda Adli,Esben Agerbo,Mareike Aichholzer,Allison Aiello,Tracy Air,Thomas Als,Erik Andersson,Till Andlauer,Volker Arolt,Helga Ask,Julia Bäckman,Sunita Badola,Clive Ballard,Karina Banasik,Nicholas Bass,Aartjan Beekman,Síntia Belangero,Tim Bigdeli,Elisabeth Binder,Ottar Bjerkeset,Gyða Björnsdóttir,Sigrid Børte,Emma Bränn,Alice Braun,Thorsten Brodersen,Tanja Brückl,Søren Brunak,Mie Bruun,Margit Burmeister,Pichit Buspavanich,Jonas Bybjerg‐Grauholm,Enda Byrne,Jianwen Cai,Archie Campbell,Megan Campbell,Adrián Campos,Enrique Castelao,Jorge Cervilla,Boris Chaumette,Chia-Yen Chen,Hsi‐Chung Chen,Zhengming Chen,Sven Cichon,Lucía Colodro‐Conde,Anne Corbett,Elizabeth Corfield,Baptiste Couvy‐Duchesne,Nick Craddock,Udo Dannlowski,Gail Davies,Eco Geus,Ian Deary,Franziska Degenhardt,Abbas Dehghan,J. DePaulo,Michael Deuschle,Maria Didriksen,Khoa Dinh,Neşe Direk,Srdjan Djurovic,Anna Docherty,Katharina Domschke,Joseph Dowsett,Ole Drange,Erin Dunn,William Eaton,Guðmundur Einarsson,Thalia Eley,Samar Elsheikh,Jan Engelmann,Michael Benros,Christian Erikstrup,Valentina Escott‐Price,Chiara Fabbri,Yu Fang,Sarah Finer,Josef Frank,Robert Free,Linda Gallo,He Gao,Michael Gill,Maria Gilles,Fernando Goes,Scott Gordon,Jakob Grove,Daníel Guðbjartsson,Blanca Gutiérrez,Tim Hahn,Lynsey Hall,Thomas Hansen,Magnús Haraldsson,Catharina Hartman,Alexandra Havdahl,Caroline Hayward,Stefanie Heilmann‐Heimbach,Stefan Herms,Ian Hickie,Henrik Hjalgrim,Jens Hjerling‐Leffler,Per Hoffmann,Georg Homuth,Carsten Horn,Jouke-Jan Hottenga,David Hougaard,Iiris Hovatta,Qin Huang,Donald Hucks,Floris Huider,Karen Hunt,Nicholas Ialongo,Marcus Ising,Erkki Isometsä,Rick Jansen,Yunxuan Jiang,Ian Jones,Lisa Jones,Lina Jönsson,Masahiro Kanai,Robert Karlsson,Siegfried Kasper,Kenneth Kendler,Ronald Kessler,Stefan Kloiber,James Knowles,Nastassja Koen,Julia Kraft,Henry Kranzler,Kristi Krebs,Theodora Kallak,Zoltán Kutalik,Elisa Lahtela,Marilyn Lake,Margit Larsen,Eric Lenze,Melissa Lewins,Glyn Lewis,Liming Li,Bochao Lin,Kuang Lin,Penelope Lind,Yu‐Li Liu,Donald MacIntyre,Dean MacKinnon,Brion Maher,Wolfgang Maier,Victoria Marshe,Gabriela Martínez-Levy,Koichi Matsuda,Hamdi Mbarek,Peter McGuffin,Sarah Medland,Susanne Meinert,Susan Mikkelsen,Yuri Milaneschi,Iona Millwood,Esther Molina,Francis Mondimore,Preben Mortensen,Benoit Mulsant,Joonas Naamanka,Jake Najman,Matthias Nauck,Igor Nenadić,Kasper Nielsen,Ilja Nolt,Merete Nordentoft,Markus Nöthen,Mette Nyegaard,Michael O’Donovan,Ásmundur Oddsson,Adrielle Oliveira,Catherine Olsen,Högni Óskarsson,Sisse Ostrowski,Michael Owen,Richard Packer,Teemu Palviainen,Pedro Pan,Carlos Pato,Michele Pato,Nancy Pedersen,Ole Pedersen,Wouter Peyrot,James Potash,Martin Preisig,M. Preuss,Jorge Quiroz,Miguel Rentería,Charles Reynolds,John Rice,Saori Sakaue,Marcos Santoro,Robert Schoevers,Andrew Schork,Thomas Schulze,Tabea Send,Jianxin Shi,Engilbert Sigurðsson,Kritika Singh,Grant Sinnamon,Lea Sirignano,Olav Smeland,Daniel Smith,Tamar Sofer,Erik Sørensen,Sundararajan Srinivasan,Hreinn Stefánsson,Kari Stefansson,Péter Straub,Mei‐Hsin Su,André Tadić,Henning Teismann,Alexander Teumer,Anita Thapar,Pippa Thomson,Lise Thørner,Apostolia Topaloudi,Shih‐Jen Tsai,Ioanna Tzoulaki,George Uhl,André Uitterlinden,Henrik Ullum,Daniel Umbricht,Robert Ursano,Sandra Auwera,Albert Hemert,Abirami Veluchamy,Alexander Viktorin,Henry Völzke,G. Walters,Xiaotong Wang,Agaz Wani,Myrna Weissman,Jürgen Wellmann,David Whiteman,Derek Wildman,Gonneke Willemsen,Alexander Williams,Bendik Winsvold,Stephanie Witt,Xiong Ying,Lea Zillich,John‐Anker Zwart,Twenty-Three Team,China Group,Estonian Team,Genes Team,HUNT Psychiatry,The Project,VA Program,Ole Andreassen,Bernhard Baune,Klaus Berger,Marcus Dörr,Anders Børglum,Gerome Breen,Na Cai,Hilary Coon,William Copeland,Byron Creese,Carlos Cruz-Fuentes,Darina Czamara,Lea Davis,Eske Derks,Enrico Domenici,Paul Elliott,Andreas Forstner,Micha Gawlik,Joel Gelernter,Hans Grabe,Steven Hamilton,Kristian Hveem,Catherine John,Jaakko Kaprio,Tilo Kircher,Marie‐Odile Krebs,Po‐Hsiu Kuo,Mikael Landén,Kelli Lehto,Douglas Levinson,Qingqin Li,Klaus Lieb,Ruth Loos,Yi Lu,Susanne Lucae,Jurjen Luykx,Hermine Maes,Patrik Magnusson,Hilary Martin,Nicholas Martin,Andrew McQuillin,Christel Middeldorp,Lili Milani,Ole Mors,Daniel Müller,Bertram Müller‐Myhsok,Yukinori Okada,Albertine Oldehinkel,Sara Paciga,Colin Palmer,Peristera Paschou,Brenda Penninx,Roy Perlis,Roseann Peterson,Giorgio Pistis,Renato Polimanti,David Porteous,Danielle Posthuma,Jill Rabinowitz,Ted Reichborn‐Kjennerud,Andreas Reif,Frances Rice,Roland Ricken,Marcella Rietschel,Margarita Rivera,Christian Rück,Giovanni Salum,Catherine Schaefer,Srijan Sen,Alessandro Serretti,Alkistis Skalkidou,Jordan Smoller,Dan Stein,Frederike Stein,Murray Stein,Patrick Sullivan,Martin Tesli,Thorgeir Thorgeirsson,Henning Tiemeier,Nicholas Timpson,Monica Uddin,Rudolf Uher,David Heel,Karin Verweij,Robin Walters,Sylvia Wassertheil‐Smoller,Jens Wendland,Thomas Werge,Aeilko Zwinderman,Karoline Kuchenbaecker,Naomi Wray,Stephan Ripke,Cathryn Lewis,Andrew McIntosh