Abstract Education sculpts specialized neural circuits for skills like reading that are critical to success in modern society but were not anticipated by the selective pressures of evolution. Does the emergence of brain regions that selectively process novel visual stimuli like words occur at the expense of cortical representations of other stimuli like faces and objects? To answer this question we conducted a randomized controlled trial with pre-school children (five years of age). We found that being taught reading versus oral language skills induced different patterns of change in category-selective regions of visual cortex. Reading instruction enhanced the response to text but did not diminish the response to other categories. How these changes play out over a longer timescale is still unknown but, based on these data, we can surmise that high-level visual cortex undergoes rapid changes as children enter school and begin establishing new skills like literacy.