We show how to coarse grain polymers in a good solvent as single particles,interacting with density-independent or density-dependent interactions. Theseinteractions can be between the centres of mass, the mid-points or end-pointsof the polymers. We also show how to extend these methods to polymers in poorsolvents and mixtures of polymers. Treating polymers as soft colloids cangreatly speed up the simulation of complex many-polymer systems, includingpolymer-colloid mixtures.