Atmospheric humidity has a big influence on the distribution and maximum intensity of precipitation, the potential intensity of tropical cyclones, surface hydrology and human heat stress. Significant increases in specific humidity — the ratio of water vapour to air in a given volume of air — have been observed at the Earth's surface, but it was not clear whether these changes are due to natural or human influences. Now, using a new data set of surface specific humidity observations, along with output from a coupled climate model, Willett et al. identify a significant increase in global mean surface specific humidity during the late twentieth century that is mainly attributable to human influence. A new dataset of surface specific humidity observations is used, along with output from a coupled climate model, to identify a significant increase in global mean surface specific humidity over the late twentieth century that is mainly attributable to human influence, indicating that human-induced climate change has already had a significant influence on this important climate variable. Water vapour is the most important contributor to the natural greenhouse effect, and the amount of water vapour in the atmosphere is expected to increase under conditions of greenhouse-gas-induced warming, leading to a significant feedback on anthropogenic climate change1,2,3. Theoretical and modelling studies predict that relative humidity will remain approximately constant at the global scale as the climate warms, leading to an increase in specific humidity1,4,5. Although significant increases in surface specific humidity have been identified in several regions6,7,8,9, and on the global scale in non-homogenized data10, it has not been shown whether these changes are due to natural or human influences on climate. Here we use a new quality-controlled and homogenized gridded observational data set of surface humidity, with output from a coupled climate model, to identify and explore the causes of changes in surface specific humidity over the late twentieth century. We identify a significant global-scale increase in surface specific humidity that is attributable mainly to human influence. Specific humidity is found to have increased in response to rising temperatures, with relative humidity remaining approximately constant. These changes may have important implications, because atmospheric humidity is a key variable in determining the geographical distribution11,12,13 and maximum intensity14 of precipitation, the potential maximum intensity of tropical cyclones15, and human heat stress16, and has important effects on the biosphere17 and surface hydrology17,18.